Document Detail


Arteriovenous differences for amino acids across control and acid-secreting rat stomach in vivo.
MedLine Citation:
PMID:  6860304     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
1. A method is described for measuring arteriovenous differences across the rat stomach in vivo. 2. Notable results were the uptake of branched-chain amino acids, the uptake of arginine, which was approximately balanced by an output of ornithine, and the output of alanine. 3. The fractional extraction of glutamine from the blood by the stomach wall of pentagastrin-stimulated rats was 4.7%. 4. The arteriovenous differences for ammonia depended upon the blood ammonia concentration. 5. Arteriovenous differences were not affected by the stimulation of acid secretion with pentagastrin. 6. It is concluded that the high activity of branched-chain-amino-acid aminotransferase (EC 2.6.1.42) in the gastric mucosa is associated with metabolism of these amino acids, but that the stomach wall is a less avid user of glutamine than is the small intestine.
Authors:
N G Anderson; P J Hanson
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  The Biochemical journal     Volume:  210     ISSN:  0264-6021     ISO Abbreviation:  Biochem. J.     Publication Date:  1983 Feb 
Date Detail:
Created Date:  1983-07-29     Completed Date:  1983-07-29     Revised Date:  2009-11-18    
Medline Journal Info:
Nlm Unique ID:  2984726R     Medline TA:  Biochem J     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  451-5     Citation Subset:  IM    
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MeSH Terms
Descriptor/Qualifier:
Amino Acids / blood,  metabolism*
Amino Acids, Branched-Chain / metabolism
Ammonia / blood
Animals
Arteries
Gastric Acid / secretion*
Gastric Mucosa / blood supply,  drug effects,  metabolism*
Male
Pentagastrin / pharmacology
Rats
Rats, Inbred Strains
Veins
Chemical
Reg. No./Substance:
0/Amino Acids; 0/Amino Acids, Branched-Chain; 5534-95-2/Pentagastrin; 7664-41-7/Ammonia
Comments/Corrections

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