Document Detail

Arteriosclerosis of penile arteries: histological findings and their significance in the treatment of erectile dysfunction.
MedLine Citation:
PMID:  12053029     Owner:  NLM     Status:  MEDLINE    
OBJECTIVES: In this pathomorphological study, location, distribution, and degree of arteriosclerotic stenoses in penile arteries from unselected cadavers are investigated. The findings are discussed in the context of penile revascularization and may explain the poor results of this form of surgery in older patients with general arteriosclerosis. MATERIALS AND METHODS: 120 penile specimens from 120 cadavers were examined histologically after van Gieson staining. Transverse sections were performed at the level of the pubic bone, in the middle of the penis, and at the sulcus coronarius. At these levels the dorsal and deep penile arteries were examined. RESULTS: We found arteriosclerotic stenoses of the penile arteries in 65% of the specimens. Of these stenotic lesions, 20.4% were situated proximally, 37.1% centrally, and 42.5% distally. CONCLUSIONS: In patients with arteriosclerotic stenoses of the penile arteries, microsurgical penile revascularization to the proximal part of the dorsal arteries at the base of the penis seems to be without any relevant long-lasting hemodynamic effect, because the blood flow will be impeded by the peripheral stenoses. This can explain the poor results of revascularization in this group of patients.
Ulrich Grein; Günter E Schubert
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Urologia internationalis     Volume:  68     ISSN:  0042-1138     ISO Abbreviation:  Urol. Int.     Publication Date:  2002  
Date Detail:
Created Date:  2002-06-07     Completed Date:  2003-02-25     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  0417373     Medline TA:  Urol Int     Country:  Switzerland    
Other Details:
Languages:  eng     Pagination:  261-4     Citation Subset:  IM    
Copyright Information:
Copyright 2002 S. Karger AG, Basel
Department of Urology and Pediatric Urology, en-süd-Klinikum, Martfeld Krankenhaus, Schwelm, Germany.
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MeSH Terms
Aged, 80 and over
Arteries / pathology
Arteriosclerosis / pathology*
Erectile Dysfunction / drug therapy,  pathology
Middle Aged
Penis / blood supply*,  pathology*

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