Document Detail


Arterial wall lesions after pulmonary embolism, especially ruptures and aneurysms.
MedLine Citation:
PMID:  956448     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
During an histological study of pulmonary thromboembolism, arterial wall splits, many associated with saccular microaneurysms, were observed in association with emboli or their fibrous residue. Other aneurysmal lesions, non-inflammatory focal medial necrosis, and medial scars were also seen in a few cases. The nature of the arterial rents indicates that they arose by mechanical splitting after acute stretching of the artery at the time of embolic impaction. Saccular aneurysms then developed in some. Impaction could also have caused the foci of medial necrosis while the medial scars could represent healed former necrosis of rupture. Though the observed incidence of lesions was relatively low, this seems to be due to their small sizes and the sampling inherent in conventional histological analysis. It is concluded that arterial splits are probably a common effect of pulmonary embolism and often give rise to small aneurysms.
Authors:
S Sevitt
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Journal of clinical pathology     Volume:  29     ISSN:  0021-9746     ISO Abbreviation:  J. Clin. Pathol.     Publication Date:  1976 Aug 
Date Detail:
Created Date:  1976-10-20     Completed Date:  1976-10-20     Revised Date:  2009-11-18    
Medline Journal Info:
Nlm Unique ID:  0376601     Medline TA:  J Clin Pathol     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  665-74     Citation Subset:  AIM; IM    
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MeSH Terms
Descriptor/Qualifier:
Adolescent
Adult
Aged
Aneurysm / pathology*
Child
Female
Humans
Male
Middle Aged
Necrosis
Pulmonary Artery / pathology*
Pulmonary Embolism / pathology*
Rupture, Spontaneous
Comments/Corrections

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