Document Detail


Arterial versus venous endothelial cells.
MedLine Citation:
PMID:  18972135     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Vascular endothelial cells (ECs) form the inner lining of all blood vessels from the largest artery and veins, viz., the aorta and venae cavae, respectively, to the capillaries that connect the arterial and venous systems. Because these two major conducting systems of the cardiovasculature differ functionally, it is not surprising that the physical makeup of arteries and veins, including the ECs that line their lumina, are also distinct. Although few would argue that the local environment contributes to the differences between arteries and veins, recent evidence has shown that the specification of arterial and venous identity is largely genetically determined.
Authors:
Nathaniel G dela Paz; Patricia A D'Amore
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Publication Detail:
Type:  Comparative Study; Journal Article; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, P.H.S.; Review     Date:  2008-10-30
Journal Detail:
Title:  Cell and tissue research     Volume:  335     ISSN:  1432-0878     ISO Abbreviation:  Cell Tissue Res.     Publication Date:  2009 Jan 
Date Detail:
Created Date:  2008-12-10     Completed Date:  2009-03-18     Revised Date:  2014-07-22    
Medline Journal Info:
Nlm Unique ID:  0417625     Medline TA:  Cell Tissue Res     Country:  Germany    
Other Details:
Languages:  eng     Pagination:  5-16     Citation Subset:  IM    
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MeSH Terms
Descriptor/Qualifier:
Animals
Arteries / cytology,  metabolism*
Endothelial Cells / cytology,  metabolism*
Humans
Organ Specificity / physiology
Veins / cytology,  metabolism*
Grant Support
ID/Acronym/Agency:
EY015435/EY/NEI NIH HHS; EY05318/EY/NEI NIH HHS; R01 EY005318/EY/NEI NIH HHS; T32 HL076115/HL/NHLBI NIH HHS

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