| Arterial and venous vessels are required for modulating developmental relocalization and laterality of the interrenal tissue in zebrafish. | |
| | |
MedLine Citation:
|
PMID: 20549735 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
During zebrafish embryogenesis, the endothelium signals to emergent bilateral interrenal primordia to converge toward the midline, yet the merged interrenal tissue has been found to be situated lateral to the midline. We show in this study that bilateral interrenal tissue clusters fused at the central midline, before relocating laterally to be juxtaposed between the dorsal aorta and the posterior cardinal vein. In ets1b morphants where the midtrunk vasculature failed to assemble, various degrees of interrenal fusion defects were displayed, and the interrenal laterality was lost. As either arterial or venous endothelium was specifically reduced, the interrenal tissue was defective in its relocalization and laterality, yet remained closely associated with the malformed vasculature. Our results showed evidence to support that assembly of the axial artery and vein, and its resulting vascular topology at the midtrunk, is required for patterning relocalization and laterality of the interrenal tissue after the initial medial fusion. |
| | |
Authors:
|
Chih-Wei Chou; Hsiao-Chu Hsu; Sue-Ing Quek; Woon-Khiong Chan; Yi-Wen Liu |
Related Documents
:
|
8754975 - External veins of the spinal cord it the wistar rats. 1244455 - Cervical venous reflux in dynamic brain scintigraphy. 2328405 - Simultaneous perfusion of rat isolated superior mesenteric arterial and venous beds: co... 9726465 - Dementia resulting from dural arteriovenous fistulas: the pathologic findings of venous... 1072545 - Acute mesenteric infarction caused by small vessel disease. 2431915 - Endothelium-dependent relaxation of human epicardial coronary arteries: frequent lack o... |
Publication Detail:
|
Type: Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
|
Title: Developmental dynamics : an official publication of the American Association of Anatomists Volume: 239 ISSN: 1097-0177 ISO Abbreviation: Dev. Dyn. Publication Date: 2010 Jul |
Date Detail:
|
Created Date: 2010-06-29 Completed Date: 2010-09-23 Revised Date: - |
Medline Journal Info:
|
Nlm Unique ID: 9201927 Medline TA: Dev Dyn Country: United States |
Other Details:
|
Languages: eng Pagination: 1995-2004 Citation Subset: IM |
Copyright Information:
|
(c) 2010 Wiley-Liss, Inc. |
Affiliation:
|
Department of Life Science, Tunghai University, No. 181 Sec. 3 Taichung-Port Road, Taichung, Taiwan, R.O.C. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Animals Arteries / embryology* In Situ Hybridization Microscopy, Confocal Veins / embryology* Zebrafish / embryology* |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: A novel role for transcription factor Lmo4 in thymus development through genetic interaction with Ci...
Next Document: Expression of Gpr177, a Wnt trafficking regulator, in mouse embryogenesis.