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Arterial thrombosis-insidious, unpredictable and deadly.
MedLine Citation:
PMID:  22064432     Owner:  NLM     Status:  In-Data-Review    
Abstract/OtherAbstract:
The formation of blood clots-thrombosis-at sites of atherosclerotic plaque rupture is a major clinical problem despite ongoing improvements in antithrombotic therapy. Progress in identifying the pathogenic mechanisms regulating arterial thrombosis has led to the development of newer therapeutics, and there is general anticipation that these treatments will have greater efficacy and improved safety. However, major advances in this field require the identification of specific risk factors for arterial thrombosis in affected individuals and a rethink of the 'one size fits all' approach to antithrombotic therapy.
Authors:
Shaun P Jackson
Publication Detail:
Type:  Journal Article     Date:  2011-11-07
Journal Detail:
Title:  Nature medicine     Volume:  17     ISSN:  1546-170X     ISO Abbreviation:  Nat. Med.     Publication Date:  2011  
Date Detail:
Created Date:  2011-11-08     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9502015     Medline TA:  Nat Med     Country:  United States    
Other Details:
Languages:  eng     Pagination:  1423-36     Citation Subset:  IM    
Affiliation:
1] Australian Centre for Blood Diseases, Alfred Medical Research and Education Precinct, Monash University, Melbourne, Australia. [2] Department of Molecular and Experimental Medicine, The Scripps Research Institute, La Jolla, California, USA.
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