Document Detail

Arterial thermodilution: an alternative to pulmonary artery catheter for cardiac output assessment in burn patients.
MedLine Citation:
PMID:  11226655     Owner:  NLM     Status:  MEDLINE    
STUDY OBJECTIVE: To study the agreement between cardiac output measurements with the pulmonary artery catheter and with the transpulmonary thermodilution technique in patients with burns.
DESIGN: Prospective, clinical study.
PATIENTS: 23 patients with serious burns and an abbreviated burn severity index score (ABSI)>6.
SETTING: intensive care unit for severely burned in a burn center in Germany.
RESULTS: A total number of 218 cardiac output measurements obtained during the first 72 h postburn were analysed. In the pulmonary artery group, mean cardiac index was 3.93 l/min/m2 and ranged from 0.96 to 9.58. In the transpulmonary group the cardiac index measurements ranged from 0.96 to 9.61 with a mean of 4.0 l/min/m2. During the entire observation period cardiac index was consistently higher in the transpulmonary group than in the pulmonary artery group with a bias of 0.32 l/min/m2 and a standard deviation (S.D.) of 0.29 l/min/m2. Linear regression analysis revealed CI(arterial)=0.98xCI(pulm)+0.22l/min/m2 (r=0.9678, P<0.038). Bias and precision to each time point according to Bland and Altman demonstrated a good agreement between both techniques.
CONCLUSION: The transpulmonary thermodilution offers an attractive, less invasive alternative to the pulmonary artery catheter in patients with burns. Arterial thermodilution for CO measurements is as precise as PA thermal dilution, and CO(pulm) can be replaced by CI(arterial) when basic methodological principles are respected.
C Holm; B Melcer; F Hörbrand; G Henckel von Donnersmarck; W Mühlbauer
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Publication Detail:
Type:  Clinical Trial; Comparative Study; Journal Article    
Journal Detail:
Title:  Burns : journal of the International Society for Burn Injuries     Volume:  27     ISSN:  0305-4179     ISO Abbreviation:  Burns     Publication Date:  2001 Mar 
Date Detail:
Created Date:  2001-03-06     Completed Date:  2001-07-05     Revised Date:  2014-07-28    
Medline Journal Info:
Nlm Unique ID:  8913178     Medline TA:  Burns     Country:  England    
Other Details:
Languages:  eng     Pagination:  161-6     Citation Subset:  IM    
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MeSH Terms
Burn Units
Burns / physiopathology*
Carbon Monoxide / analysis*
Cardiac Output*
Catheterization, Swan-Ganz / methods*
Injury Severity Score
Linear Models
Middle Aged
Monitoring, Physiologic / methods
Prospective Studies
Reproducibility of Results
Sensitivity and Specificity
Thermodilution / methods*
Reg. No./Substance:
7U1EE4V452/Carbon Monoxide

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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