Document Detail

Arterial structural changes in hypertension: a consideration of methodology, terminology and functional consequence.
MedLine Citation:
PMID:  14691336     Owner:  NLM     Status:  MEDLINE    
Alteration of resistance artery geometric design is a hallmark of established hypertension. In particular, there is an increased media thickness: lumen diameter ratio. In this review, consideration is given to the methods available for assessment of vascular structure, the terminology used to describe vascular structural changes in hypertension and the possible functional consequences of altered arterial design in the maintenance of the hypertensive state. In light of these considerations, a number of proposals are made concerning quantification strategies and descriptor terminologies. In particular, a simple descriptor terminology is proposed that describes such structural differences but makes no assumptions concerning the underlying processes that account for altered arterial structure in hypertension.
Stuart J Bund; Robert M K W Lee
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't; Review     Date:  2003-12-22
Journal Detail:
Title:  Journal of vascular research     Volume:  40     ISSN:  1018-1172     ISO Abbreviation:  J. Vasc. Res.     Publication Date:    2003 Nov-Dec
Date Detail:
Created Date:  2004-01-27     Completed Date:  2004-02-26     Revised Date:  2008-11-21    
Medline Journal Info:
Nlm Unique ID:  9206092     Medline TA:  J Vasc Res     Country:  Switzerland    
Other Details:
Languages:  eng     Pagination:  547-57     Citation Subset:  IM    
Copyright Information:
Copyright 2003 S. Karger AG, Basel
Department of Human Anatomy and Physiology, Conway Institute of Biomolecular and Biomedical Research, University College Dublin, Dublin, Ireland.
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MeSH Terms
Arteries / pathology*,  physiopathology*
Cardiovascular Physiological Phenomena
Hypertension / pathology*,  physiopathology*
Terminology as Topic
Comment In:
J Vasc Res. 2003 Nov-Dec;40(6):558-60   [PMID:  14691337 ]

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