Document Detail


Arterial spin-labeling in routine clinical practice, part 3: hyperperfusion patterns.
MedLine Citation:
PMID:  18356466     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Arterial spin-labeled (ASL) perfusion imaging can be implemented successfully into a routine clinical neuroimaging protocol and can accurately demonstrate alterations in brain perfusion. We have observed patterns of focal, regional, and global hyperperfusion in a wide variety of disease processes. The causes of hyperperfusion at clinical ASL have not been previously characterized. Focal lesions such as brain tumors and vascular malformations with increased perfusion can be well depicted by ASL. More global causes of hyperperfusion, including postanoxia vasodilation and hypercapnia, may go undetected on conventional MR images, whereas the regional hyperperfusion, which may occur in reversible encephalopathies and luxury perfusion, has been consistently illustrated on ASL cerebral blood flow maps at our institution.
Authors:
A R Deibler; J M Pollock; R A Kraft; H Tan; J H Burdette; J A Maldjian
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Publication Detail:
Type:  Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Review     Date:  2008-03-20
Journal Detail:
Title:  AJNR. American journal of neuroradiology     Volume:  29     ISSN:  1936-959X     ISO Abbreviation:  AJNR Am J Neuroradiol     Publication Date:  2008 Sep 
Date Detail:
Created Date:  2008-09-10     Completed Date:  2008-11-24     Revised Date:  2010-04-29    
Medline Journal Info:
Nlm Unique ID:  8003708     Medline TA:  AJNR Am J Neuroradiol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  1428-35     Citation Subset:  IM    
Affiliation:
Department of Radiology, Wake Forest University School of Medicine, Winston-Salem, NC 27157, USA.
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MeSH Terms
Descriptor/Qualifier:
Aged
Aged, 80 and over
Brain / blood supply*,  pathology*
Cerebral Arteries / pathology*
Cerebrovascular Disorders / pathology*
Child
Female
Humans
Male
Spin Labels
Grant Support
ID/Acronym/Agency:
EB003880/EB/NIBIB NIH HHS; EB004673/EB/NIBIB NIH HHS; EB004673-02S2/EB/NIBIB NIH HHS
Chemical
Reg. No./Substance:
0/Spin Labels

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