| Arterial spin labeling of cerebral perfusion territories using a separate labeling coil. | |
| | |
MedLine Citation:
|
PMID: 18425844 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
PURPOSE: To obtain cerebral perfusion territories of the left, the right, and the posterior circulation in humans with high signal-to-noise ratio (SNR) and robust delineation. MATERIALS AND METHODS: Continuous arterial spin labeling (CASL) was implemented using a dedicated radio frequency (RF) coil, positioned over the neck, to label the major cerebral feeding arteries in humans. Selective labeling was achieved by flow-driven adiabatic fast passage and by tilting the longitudinal labeling gradient about the Y-axis by theta = +/- 60 degrees . RESULTS: Mean cerebral blood flow (CBF) values in gray matter (GM) and white matter (WM) were 74 +/- 13 mL . 100 g(-1) . minute(-1) and 14 +/- 13 mL . 100 g(-1) . minute(-1), respectively (N = 14). There were no signal differences between left and right hemispheres when theta = 0 degrees (P > 0.19), indicating efficient labeling of both hemispheres. When theta = +60 degrees , the signal in GM on the left hemisphere, 0.07 +/- 0.06%, was 92% lower than on the right hemisphere, 0.85 +/- 0.30% (P < 1 x 10(-9)), while for theta = -60 degrees , the signal in the right hemisphere, 0.16 +/- 0.13%, was 82% lower than on the contralateral side, 0.89 +/- 0.22% (P < 1 x 10(-10)). Similar attenuations were obtained in WM. CONCLUSION: Clear delineation of the left and right cerebral perfusion territories was obtained, allowing discrimination of the anterior and posterior circulation in each hemisphere. |
| | |
Authors:
|
Fernando F Paiva; Alberto Tannús; S Lalith Talagala; Afonso C Silva |
Related Documents
:
|
1546544 - Cycloid psychosis: regional cerebral blood flow correlates of a psychotic episode. 6799314 - Changes in brain blood flow associated with deltamethrin-induced choreoathetosis in the... 20623294 - The overlap between neurodegenerative and vascular factors in the pathogenesis of demen... 3488244 - Age and learning: experimental and clinical aspects. 19365024 - Effect of unoprostone on topographic and blood flow changes in the ischemic optic nerve... 2334074 - Indications for placement of drains in the splenic fossa. |
Publication Detail:
|
Type: Journal Article; Research Support, N.I.H., Intramural |
Journal Detail:
|
Title: Journal of magnetic resonance imaging : JMRI Volume: 27 ISSN: 1053-1807 ISO Abbreviation: J Magn Reson Imaging Publication Date: 2008 May |
Date Detail:
|
Created Date: 2008-04-28 Completed Date: 2008-08-26 Revised Date: - |
Medline Journal Info:
|
Nlm Unique ID: 9105850 Medline TA: J Magn Reson Imaging Country: United States |
Other Details:
|
Languages: eng Pagination: 970-7 Citation Subset: IM |
Copyright Information:
|
(c) 2008 Wiley-Liss, Inc. |
Affiliation:
|
Cerebral Microcirculation Unit, Laboratory of Functional and Molecular Imaging, National Institute of Neurological Disorders and Stroke (NINDS), National Institutes of Health (NIH), Bethesda, Maryland, USA. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Adult Cerebral Arteries / anatomy & histology* Cerebrovascular Circulation* Female Humans Image Processing, Computer-Assisted Magnetic Resonance Angiography / instrumentation* Male Spin Labels* |
| Chemical | |
Reg. No./Substance:
|
0/Spin Labels |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Gadolinium-based contrast agents and their potential role in the pathogenesis of nephrogenic systemi...
Next Document: Effect of intramyocardial bone marrow cell injection on diastolic function in patients with chronic ...