| Arterial reconstruction in the ischemic hand and wrist: effects on microvascular physiology and health-related quality of life. | |
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MedLine Citation:
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PMID: 9763249 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Patients were evaluated before and after arterial reconstruction surgery (1) to define the physiology of the digital microcirculation in chronic subcritical ischemia, (2) to demonstrate the short-term effects of successful arterial reconstruction on microvascular flow, and (3) to document the effects of surgery on symptoms, function, and health-related quality of life. Arterial insufficiency was the result of a proximal reconstructible occlusive lesion, 1 or more distal unreconstructible occlusions, and secondary reactive vasospasm. Microvascular physiology was evaluated by monitoring digital temperatures, microvascular perfusion (laser Doppler fluxmetry) and perfusion patterns (laser Doppler perfusion patterns (laser Doppler perfusion imaging). Following successful vascular reconstruction, digital temperatures and microvascular perfusion improved significantly, approaching control levels. Although cold sensitivity was unchanged, symptoms decreased and upper extremity function and health-related quality of life improved after successful proximal reconstruction in patients with 2-level arterial occlusion. |
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Authors:
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L A Koman; D S Ruch; M Aldridge; B P Smith; M B Holden; M Fulcher |
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Publication Detail:
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Type: Clinical Trial; Journal Article; Research Support, U.S. Gov't, P.H.S. |
Journal Detail:
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Title: The Journal of hand surgery Volume: 23 ISSN: 0363-5023 ISO Abbreviation: J Hand Surg Am Publication Date: 1998 Sep |
Date Detail:
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Created Date: 1998-12-22 Completed Date: 1998-12-22 Revised Date: 2009-06-08 |
Medline Journal Info:
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Nlm Unique ID: 7609631 Medline TA: J Hand Surg Am Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 773-82 Citation Subset: IM |
Affiliation:
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Department of Orthopaedic Surgery, Wake Forest University School of Medicine, Winston-Salem, NC 27157-1070, USA. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adult Analysis of Variance Anastomosis, Surgical / methods Cohort Studies Female Fingers / blood supply* Follow-Up Studies Hand / blood supply* Humans Ischemia / surgery* Laser-Doppler Flowmetry Male Microcirculation / physiology Middle Aged Quality of Life* Radial Artery / pathology, surgery Treatment Outcome Ulnar Artery / pathology, surgery Vascular Patency / physiology Vascular Surgical Procedures / methods Wrist / blood supply* |
| Grant Support | |
ID/Acronym/Agency:
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AR41765/AR/NIAMS NIH HHS |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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