| Arterial-pulse oximetry loops: a new method of monitoring vascular tone. | |
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MedLine Citation:
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PMID: 9269615 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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OBJECTIVE: We report the off-line calculation of the vascular compliance of the finger and suggest the continuous on-line use of this methodology as an aid to monitoring the peripheral vascular resistance. This method consists of the simultaneous analysis of the waveform signals from the pulse oximeter monitors and the arterial pressure as indicators of "volume" and pressure respectively to continuously calculate the vascular "compliance" (volume change per unit pressure change). This should be seen as a "relative compliance" as the pulse plethysmograph signal is not calibrated. This new methodology allows for continuous monitoring of peripheral vascular compliance as a beat-to-beat indicator of peripheral vascular resistance. The vaso-constrictors, phenylephrine and ephedrine, were shown to decrease the compliance as predicted. METHODS: The arterial pressure and pulse oximeter waveforms were obtained during routine anesthetic care. The waveforms were collected with a computer data-acquisition system and then analyzed "off-line" as an indirect indicator of total vascular tone. Demographic and clinical information including drug administration were recorded. RESULTS: A case report is presented using this new form of analysis. Vascular compliance changes induced by phenylephrine and ephedrine were studied. A dose response curve of peripheral vascular compliance to phenylephrine was generated from these data. CONCLUSIONS: By plotting the pulse oximeter waveforms versus the arterial waveforms, multiple volume versus pressure (relative compliance) loops were obtained. Analysis of these loops may assist in the monitoring of vascular compliance. |
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Authors:
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K H Shelley; W B Murray; D Chang |
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Publication Detail:
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Type: Case Reports; Journal Article |
Journal Detail:
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Title: Journal of clinical monitoring Volume: 13 ISSN: 0748-1977 ISO Abbreviation: J Clin Monit Publication Date: 1997 Jul |
Date Detail:
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Created Date: 1997-10-16 Completed Date: 1997-10-16 Revised Date: 2004-11-17 |
Medline Journal Info:
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Nlm Unique ID: 8506707 Medline TA: J Clin Monit Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 223-8 Citation Subset: IM |
Affiliation:
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Department of Anesthesiology, Pennsylvania State University, College of Medicine, Hershey 17033, USA. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adrenergic alpha-Agonists
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administration & dosage,
therapeutic use Anesthesia, Intravenous Arteries Blood Pressure / physiology Blood Volume / physiology Calibration Cephalometry Dose-Response Relationship, Drug Ephedrine / administration & dosage, therapeutic use Female Fingers / blood supply Forecasting Heart Rate Humans Hypotension / drug therapy, etiology Intraoperative Complications / drug therapy Meningioma / surgery Middle Aged Monitoring, Physiologic / instrumentation, methods* Online Systems Oximetry / instrumentation, methods* Phenylephrine / administration & dosage, therapeutic use Plethysmography Signal Processing, Computer-Assisted Vascular Resistance / drug effects, physiology* Vasoconstrictor Agents / administration & dosage, therapeutic use Vasomotor System / drug effects, physiology |
| Chemical | |
Reg. No./Substance:
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0/Adrenergic alpha-Agonists; 0/Vasoconstrictor Agents; 299-42-3/Ephedrine; 59-42-7/Phenylephrine |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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