| Arterial pressure, cardiac output and exercise hyperemia in chemically sympathectomized rats. | |
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MedLine Citation:
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PMID: 7312565 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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This study showed that arterial blood pressure of chemically sympathectomized rats (SR) was decreased, whereas heart rate was increased relative to controls. The cardiac output in SR was higher than that in intact animals (by 36% under urethane anaesthesia and by 80% without anaesthesia). The total peripheral resistance of SR was 1.7 times less than normal, although the magnitude of the structural component of resistance was increased. The half-time clearance of 133Xe from skeletal muscle during motor nerve stimulation was greater in SR than in intact rats by a factor of 2. It is concluded that the number of small resistance vessels in SR is low, while the lumen of individual vessels is greater than in controls, thus giving rise to an insufficient "vasodilator reserve". |
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Authors:
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I M Rodionov; V B Koshelev; A Mukhammedov; O L Vinogradova; V V Suchkov; O S Medvedev; V S Baranov |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Pflügers Archiv : European journal of physiology Volume: 391 ISSN: 0031-6768 ISO Abbreviation: Pflugers Arch. Publication Date: 1981 Oct |
Date Detail:
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Created Date: 1982-02-12 Completed Date: 1982-02-12 Revised Date: 2008-11-21 |
Medline Journal Info:
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Nlm Unique ID: 0154720 Medline TA: Pflugers Arch Country: GERMANY, WEST |
Other Details:
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Languages: eng Pagination: 324-6 Citation Subset: IM |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Animals Blood Pressure / drug effects* Cardiac Output / drug effects* Hindlimb / physiology Hydroxydopamines / pharmacology Hyperemia / physiopathology* Physical Exertion* Rats Rats, Inbred Strains Sympathectomy, Chemical* Vascular Resistance / drug effects |
| Chemical | |
Reg. No./Substance:
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0/Hydroxydopamines |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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