Document Detail

Arterial pH and arterial oxygenation are not essential for risk stratification in perforation peritonitis.
MedLine Citation:
PMID:  10063737     Owner:  NLM     Status:  MEDLINE    
BACKGROUND: The Acute Physiology and Chronic Health Evaluation (APACHE II) scoring system is widely used for assessing the severity of disease and prognostication in cases of perforation peritonitis. Investigations like arterial pH and oxygenation (PaO2), which are considered important in APACHE II, are not available in most hospitals. We therefore attempted to validate a modified APACHE II (without arterial pH and oxygenation) in cases of perforation peritonitis. METHODS: Fifty consecutive patients with perforation peritonitis admitted in the general surgical ward were prospectively analyzed vis-a-vis risk factors and mortality according to the modified APACHE II. RESULTS: The mean modified APACHE II score of those who died was 15.3 (SD 5.7) as compared to 6.6 (4.7) (p < 0.001) in those who survived. As the score increased, mortality rate rose (p < 0.001). When the score was greater than 15, mortality was 88.9%; there was 100% mortality with score greater than 17. CONCLUSION: The modified APACHE II, excluding arterial pH and oxygenation, is simplified, reliable and objective for prediction of outcome in perforation peritonitis.
S Agrawal; D Sharma; V K Raina
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Indian journal of gastroenterology : official journal of the Indian Society of Gastroenterology     Volume:  18     ISSN:  0254-8860     ISO Abbreviation:  Indian J Gastroenterol     Publication Date:    1999 Jan-Mar
Date Detail:
Created Date:  1999-04-07     Completed Date:  1999-04-07     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  8409436     Medline TA:  Indian J Gastroenterol     Country:  INDIA    
Other Details:
Languages:  eng     Pagination:  5-6     Citation Subset:  IM    
Department of Surgery, Government Medical College, Jabalpur.
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MeSH Terms
Hydrogen-Ion Concentration
Intestinal Perforation / complications*
Middle Aged
Oxygen / blood*
Peritonitis / blood,  etiology,  mortality,  physiopathology*
Prospective Studies
Risk Factors
Sensitivity and Specificity
Reg. No./Substance:

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