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Arterial flow characteristics in the presence of vascular disease and implications for fast spin echo-based noncontrast MR angiography.
MedLine Citation:
PMID:  21959828     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
PURPOSE: To investigate arterial flow characteristics in the setting of vascular disease, and examine their effect on the performance of fast spin-echo (FSE)-based noncontrast MR angiography (NC-MRA). MATERIALS AND METHODS: Seventeen patients were recruited from among those scheduled for routine contrast-enhanced MR angiography (CE-MRA) of the lower extremities at 1.5 Tesla. The research portion of the exam was performed before the clinically-indicated protocol and included phase-contrast imaging at multiple levels in the legs and FSE-based NC-MRA in the calf and thigh, using a three-dimensional ECG-gated technique that exploits differences in arterial flow velocity between diastole and systole. RESULTS: Vascular occlusions were associated with reduced systolic velocity, a delayed systolic peak, and, in two middle-aged patients, an increase in diastolic velocity. Elevated systolic and diastolic velocities were observed in a subject with a nonhealing ulcer. NC-MRA allowed visualization of arteries with systolic velocities as low as 3 cm/s, and exhibited comparable depiction to CE-MRA for diastolic velocities as high as 6 cm/s. At the highest diastolic velocities observed (15 cm/s) arterial depiction was severely degraded. CONCLUSION: FSE-based NC-MRA as presently implemented performs successfully over a wide range of flow patterns, but does not accommodate extremely low systolic velocities or very high diastolic velocities. J. Magn. Reson. Imaging 2011;. © 2011 Wiley-Liss, Inc.
Authors:
Pippa Storey; Ruth P Lim; Sooah Kim; David R Stoffel; Vivian S Lee
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Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2011-9-29
Journal Detail:
Title:  Journal of magnetic resonance imaging : JMRI     Volume:  -     ISSN:  1522-2586     ISO Abbreviation:  -     Publication Date:  2011 Sep 
Date Detail:
Created Date:  2011-9-30     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9105850     Medline TA:  J Magn Reson Imaging     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Copyright Information:
Copyright © 2011 Wiley-Liss, Inc.
Affiliation:
Radiology Department, New York University School of Medicine, New York, USA. pippa.storey@nyumc.org.
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