Document Detail


Arterial elasticity in American Indian and Caucasian children, adolescents, and young adults.
MedLine Citation:
PMID:  21828174     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
We compared arterial elasticity in American Indian and Caucasian children, adolescents, and young adults, and we assessed whether demographic, body composition, and ambulatory activity measures were predictive of arterial elasticity within each group. Fifty-one American Indians and 66 Caucasians between the ages of 8 and 30 years were assessed on large artery elasticity index, small artery elasticity index, body fat percentage, and daily ambulatory activity during 7 consecutive days. American Indians had a higher percentage of body fat than Caucasians (p = 0.002), whereas daily ambulatory activity measures were similar (p > 0.05). American Indians had a 16% lower large artery elasticity index (p = 0.007) and a 19% lower small artery elasticity index (p < 0.001) than Caucasians. The regression model for large artery elasticity index included average cadence (p = 0.001), fat-free mass (p < 0.001), age component (Caucasian only) (p < 0.001), and sex (p = 0.025). The regression model for small artery elasticity index included fat-free mass (p < 0.001), maximum cadence for 30 continuous minutes (p = 0.009), race (p = 0.005), and average cadence (p = 0.049). Between 8 and 30 years of age, elasticity means for the large and small arteries is lower in American Indians than in Caucasians. A smaller difference was observed in children, with a trend to a much larger difference in young adults. Furthermore, greater fat-free mass and higher daily ambulatory cadence are associated with higher arterial elasticity in both American Indians and Caucasians.
Authors:
Andrew W Gardner; Donald E Parker
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Publication Detail:
Type:  Comparative Study; Journal Article; Research Support, N.I.H., Extramural    
Journal Detail:
Title:  Vascular medicine (London, England)     Volume:  16     ISSN:  1477-0377     ISO Abbreviation:  Vasc Med     Publication Date:  2011 Aug 
Date Detail:
Created Date:  2011-08-10     Completed Date:  2011-12-13     Revised Date:  2013-08-27    
Medline Journal Info:
Nlm Unique ID:  9610930     Medline TA:  Vasc Med     Country:  England    
Other Details:
Languages:  eng     Pagination:  275-83     Citation Subset:  IM    
Affiliation:
CMRI Diabetes and Metabolic Research Program, Harold Hamm Oklahoma Diabetes Center, University of Oklahoma Health Sciences Center, Oklahoma City, OK 73117, USA. andrew-gardner@ouhsc.edu
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MeSH Terms
Descriptor/Qualifier:
Actigraphy
Adiposity / ethnology
Adolescent
Adult
Age Factors
Aging / ethnology*
Analysis of Variance
Chi-Square Distribution
Child
Cross-Sectional Studies
Elasticity
European Continental Ancestry Group / statistics & numerical data*
Hemodynamics*
Humans
Indians, North American / statistics & numerical data*
Linear Models
Motor Activity
Oklahoma / epidemiology
Radial Artery / physiology*,  ultrasonography
Young Adult
Grant Support
ID/Acronym/Agency:
M01-RR-14467/RR/NCRR NIH HHS; P20 MD000528/MD/NIMHD NIH HHS; P20-MD-000528-05/MD/NIMHD NIH HHS
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