| Arterial compliance and distensibility in spontaneously hypertensive rats. | |
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MedLine Citation:
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PMID: 1432334 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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AIM: These studies were undertaken in intact spontaneously hypertensive rats (SHR) to assess whether the elastic behavior of conduit arteries changes as a function of age. METHODS: We studied 16-week-old (n = 10) and 36-week-old (n = 10) SHR under fluothane anesthesia. Diameter-, compliance-, and distensibility-pressure curves were established non-invasively for the carotid artery by means of a high-precision ultrasonic echo-tracking device. Intra-arterial pressure was monitored simultaneously in the contralateral carotid artery. RESULTS: Mean blood pressure was 197 +/- 6 and 185 +/- 3 mmHg (mean +/- SEM) in the younger and older SHR, respectively. No significant difference was observed between the two groups of rats in the diameter-, compliance- and distensibility-pressure curves. CONCLUSIONS: These results suggest that the elastic behavior of elastic arteries is not necessarily altered with aging in rats with genetic hypertension. |
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Authors:
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B Waeber; D Hayoz; D Evéquoz; H R Brunner |
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Publication Detail:
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Type: Comparative Study; Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
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Title: Journal of hypertension. Supplement : official journal of the International Society of Hypertension Volume: 10 ISSN: 0952-1178 ISO Abbreviation: J Hypertens Suppl Publication Date: 1992 Aug |
Date Detail:
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Created Date: 1992-12-01 Completed Date: 1992-12-01 Revised Date: 2006-11-15 |
Medline Journal Info:
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Nlm Unique ID: 8501422 Medline TA: J Hypertens Suppl Country: ENGLAND |
Other Details:
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Languages: eng Pagination: S79-81 Citation Subset: IM |
Affiliation:
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Hypertension Division, University Hospital, Lausanne, Switzerland. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Age Factors Animals Blood Pressure Carotid Artery, External / anatomy & histology, physiology*, ultrasonography Compliance* Rats Rats, Inbred SHR / physiology* |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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