Document Detail

Arterial blood pressure in adult Nigerians with sickle cell anemia.
MedLine Citation:
PMID:  20727714     Owner:  NLM     Status:  In-Process    
AIM AND OBJECTIVE: This study was aimed at comparing the arterial blood pressures in steady state adult sickle cell patients with those of age- and sex-matched healthy controls.
METHODS: A descriptive cross-sectional study of 62 sickle cell anemia patients and 62 age- and sex-matched healthy controls was carried out in the adult outpatient sickle cell clinics and the cardiac center of the University of Nigeria Teaching Hospital (UNTH), Enugu, Nigeria. Brachial blood pressures were measured in the right arm in all subjects.
RESULTS: Significant increase in pulse rate was found in the study subjects (87.68 ± 8.91 bpm) compared with the controls (72.13 ± 6.79 bpm) (p<0.05). The mean systolic blood pressure was comparable in the two groups. However, the patients had significantly lower diastolic blood pressure, lower mean arterial blood pressure, as well as a higher pulse pressure than the control subjects. Significant correlations were found between blood pressure indices and hematocrit, body mass index, frequency of crisis, and body surface area.
CONCLUSION: Relatively lower arterial blood pressure is a significant finding in patients with sickle cell anemia. Hematocrit, frequency of crisis, body mass index, and body surface area are significant determinants of blood pressure indices in sickle cell anemia.
N I Oguanobi; B J C Onwubere; O G Ibegbulam; S O Ike; B C Anisiuba; E C Ejim; O Agwu
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Publication Detail:
Type:  Journal Article     Date:  2010-08-19
Journal Detail:
Title:  Journal of cardiology     Volume:  56     ISSN:  1876-4738     ISO Abbreviation:  J Cardiol     Publication Date:  2010 Nov 
Date Detail:
Created Date:  2010-11-03     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8804703     Medline TA:  J Cardiol     Country:  Netherlands    
Other Details:
Languages:  eng     Pagination:  326-31     Citation Subset:  IM    
Copyright Information:
Copyright © 2010 Japanese College of Cardiology. Published by Elsevier Ltd. All rights reserved.
Department of Medicine, University of Nigeria Teaching Hospital, Enugu, Nigeria.
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