Document Detail


Arterial aneurysms in patients infected with human immunodeficiency virus: a distinct clinicopathology entity?
MedLine Citation:
PMID:  10194486     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Arterial aneurysms have only recently been associated with the human immunodeficiency virus (HIV). The clinical and pathological features of 10 HIV-positive patients with arterial aneurysms were retrospectively evaluated. These aneurysms were unusual in that they affected young black patients, occurred in atypical sites, and tended toward multiplicity. Surgery was performed in eight patients. Acute and chronic inflammatory changes were revealed by means of histologic examination of the aneurysm walls, with occlusion of the vasa vasora by inflammatory infiltrate or edema being a prominent feature. Culture of the aneurysm wall or thrombus yielded positive results in two patients. The association between HIV and aneurysms may be coincidental, caused by direct viral action or by bacterial infection resulting from immunosuppression. Implications for therapy are discussed, and the need for further study is highlighted.
Authors:
R Nair; A Abdool-Carrim; R Chetty; J Robbs
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Journal of vascular surgery     Volume:  29     ISSN:  0741-5214     ISO Abbreviation:  J. Vasc. Surg.     Publication Date:  1999 Apr 
Date Detail:
Created Date:  1999-05-05     Completed Date:  1999-05-05     Revised Date:  2012-10-03    
Medline Journal Info:
Nlm Unique ID:  8407742     Medline TA:  J Vasc Surg     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  600-7     Citation Subset:  IM; X    
Affiliation:
Metropolitan Vascular Service and Department of Pathology, University of Natal Medical School, Congella, South Africa.
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MeSH Terms
Descriptor/Qualifier:
Adolescent
Adult
Aneurysm / complications*,  pathology
Arteries / pathology
Female
HIV Infections / complications*
Humans
Male
Middle Aged
Retrospective Studies

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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