| Arterial spin labeling blood flow MRI: its role in the early characterization of Alzheimer's disease. | |
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MedLine Citation:
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PMID: 20413865 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Arterial spin labeling (ASL) enables the noninvasive, quantitative imaging of cerebral blood flow using standard magnetic resonance imaging (MRI) equipment. Because it requires no contrast injection, ASL can add resting functional information to MRI studies measuring atrophy and signs of ischemic injury. Key features of ASL technology that may affect studies in Alzheimer's disease are described. The existing literature describing ASL blood flow imaging applied to Alzheimer's disease and related dementia is reviewed, and the potential role of ASL in treatment and prevention studies of early Alzheimer's disease is discussed. |
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Authors:
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David C Alsop; Weiying Dai; Murray Grossman; John A Detre |
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Publication Detail:
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Type: Journal Article; Review |
Journal Detail:
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Title: Journal of Alzheimer's disease : JAD Volume: 20 ISSN: 1875-8908 ISO Abbreviation: J. Alzheimers Dis. Publication Date: 2010 |
Date Detail:
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Created Date: 2010-06-10 Completed Date: 2010-09-08 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 9814863 Medline TA: J Alzheimers Dis Country: Netherlands |
Other Details:
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Languages: eng Pagination: 871-80 Citation Subset: IM |
Affiliation:
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Department of Radiology, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, MA 02215, USA. dalsop@bidmc.harvard.edu |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Alzheimer Disease
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metabolism*,
pathology* Arteries / physiopathology* Cerebrovascular Circulation / physiology* Humans Magnetic Resonance Imaging / methods* Spin Labels |
| Chemical | |
Reg. No./Substance:
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0/Spin Labels |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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