Document Detail


Arterial Pressure Monitoring in Mice.
MedLine Citation:
PMID:  21686061     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
The use of mice for the evaluation and study of cardiovascular pathophysiology is growing rapidly, primarily due to the relative ease for developing genetically engineered mouse models. Arterial pressure monitoring is central to the evaluation of the phenotypic changes associated with cardiovascular pathology and interventions in these transgenic and knockout models. There are four major techniques for measuring arterial pressure in the mouse: tail cuff system, implanted fluid filled catheters, Millar catheters and implanted telemetry systems. Here we provide protocols for their use and discuss the advantages and limitations for each of these techniques .
Authors:
Xin Zhao; David Ho; Shumin Gao; Chull Hong; Dorothy E Vatner; Stephen F Vatner
Publication Detail:
Type:  JOURNAL ARTICLE    
Journal Detail:
Title:  Current protocols in mouse biology     Volume:  1     ISSN:  2161-2617     ISO Abbreviation:  -     Publication Date:  2011  
Date Detail:
Created Date:  2011-6-20     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101560384     Medline TA:  Curr Protoc Mouse Biol     Country:  -    
Other Details:
Languages:  ENG     Pagination:  105-122     Citation Subset:  -    
Affiliation:
Department of Cell Biology & Molecular Medicine and the Cardiovascular Research Institute at the University of Medicine & Dentistry of New Jersey, New Jersey Medical School, 185 South Orange Avenue, MSB G609, Newark, NJ 07103, USA.
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Descriptor/Qualifier:
Grant Support
ID/Acronym/Agency:
P01 AG027211-05//NIA NIH HHS; P01 HL059139-10//NHLBI NIH HHS; P01 HL069020-10//NHLBI NIH HHS; P20 HL101420-02//NHLBI NIH HHS; R01 HL033107-27//NHLBI NIH HHS; R01 HL093481-03//NHLBI NIH HHS; R01 HL095888-04//NHLBI NIH HHS; R01 HL102472-02//NHLBI NIH HHS; R41 DK083826-01A1//NIDDK NIH HHS

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