Document Detail

Arterial patency after repeated hepatic artery bland particle embolization.
MedLine Citation:
PMID:  20188589     Owner:  NLM     Status:  MEDLINE    
PURPOSE: To evaluate hepatic arterial patency after serial bland particle embolization procedures in patients with hepatocellular carcinoma (HCC). MATERIALS AND METHODS: All patients with HCC who underwent five or more hepatic artery bland embolization procedures with permanent particulate and spherical embolic agents between September 1996 and December 2007 were retrospectively reviewed. Data analyzed included patient demographics, vessels embolized, embolic agent used, and duration of arterial patency. RESULTS: Forty-three patients were identified who underwent five or more bland embolization procedures in the same arterial distribution. Of the 43 patients examined, 83% (n = 36) showed no change in the hepatic arterial tree after repeated bland embolization (mean treatment period of 48 months +/- 23). Six patients (13%) exhibited occlusion of a fifth-order or more distal vessel after an average of 5 embolizations +/- 2 over a period of 34 months +/- 27. A single case of vascular occlusion of a fourth-order vessel was observed after five embolizations over a period of 52 months. CONCLUSIONS: Repeated bland embolization of the hepatic arteries in HCC preserves patency of the hepatic arterial vasculature despite the fact that embolization is carried out to complete stasis.
Joseph P Erinjeri; Husam M Salhab; Anne M Covey; George I Getrajdman; Karen T Brown
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Publication Detail:
Type:  Clinical Trial; Journal Article     Date:  2010-02-25
Journal Detail:
Title:  Journal of vascular and interventional radiology : JVIR     Volume:  21     ISSN:  1535-7732     ISO Abbreviation:  J Vasc Interv Radiol     Publication Date:  2010 Apr 
Date Detail:
Created Date:  2010-03-29     Completed Date:  2010-07-16     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9203369     Medline TA:  J Vasc Interv Radiol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  522-6     Citation Subset:  IM    
Copyright Information:
Copyright 2010 SIR. Published by Elsevier Inc. All rights reserved.
Department of Radiology, Memorial Sloan-Kettering Cancer Center, New York, NY 10065, USA.
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MeSH Terms
Aged, 80 and over
Carcinoma, Hepatocellular / radiography,  therapy*
Chemoembolization, Therapeutic / methods*
Dose-Response Relationship, Drug
Hepatic Artery / drug effects*,  radiography
Liver Neoplasms / radiography,  therapy*
Middle Aged
Polyvinyl Alcohol / administration & dosage*
Treatment Outcome
Vascular Patency*
Young Adult
Reg. No./Substance:
9002-89-5/Polyvinyl Alcohol

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