| Arsenic exposure in pregnancy: a population-based study in Matlab, Bangladesh. | |
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MedLine Citation:
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PMID: 17195565 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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This study assessed the exposure of pregnant women to arsenic in Matlab, Bangladesh, an area with highly-elevated concentrations of arsenic in tubewells, by measuring concentrations of arsenic in urine. In a defined administrative area, all new pregnancies were identified by urine test in gestational week 6-8, and women were asked to participate in the assessment of arsenic exposure. Urine for analysis of arsenic was collected immediately and in gestational week 30. In total, 3,426 pregnant women provided urine samples during January 2002-March 2003. There was a considerable variation in urinary concentrations of arsenic (total range 1-1,470 microg/L, adjusted to specific gravity 1.012 g/mL), with an overall median concentration of 80 microg/L (25th and 75th percentiles were 37 and 208 microg/L respectively). Similar concentrations were found in gestational week 30, indicating no trend of decreasing exposure, despite the initiation of mitigation activities in the area. Arsenic exposure was negatively associated with socioeconomic classes and achieved educational level. There were marked geographical variations in exposure. The results emphasize the urgent need for efficient mitigation activities and investigations of arsenic-related reproductive effects. |
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Authors:
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Marie E Vahter; Li Li; Barbro Nermell; Anisur Rahman; Shams El Arifeen; Mahfuzar Rahman; Lars Ake Persson; Eva-Charlotte Ekström |
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Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
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Title: Journal of health, population, and nutrition Volume: 24 ISSN: 1606-0997 ISO Abbreviation: J Health Popul Nutr Publication Date: 2006 Jun |
Date Detail:
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Created Date: 2007-01-01 Completed Date: 2007-02-13 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 100959228 Medline TA: J Health Popul Nutr Country: Bangladesh |
Other Details:
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Languages: eng Pagination: 236-45 Citation Subset: IM |
Affiliation:
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Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden. marie.vahter@ki.se |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adolescent Adult Arsenic / adverse effects*, analysis, metabolism Arsenic Poisoning / epidemiology, etiology*, urine Bangladesh Educational Status Environmental Exposure / adverse effects*, analysis Epidemiologic Studies Female Humans Middle Aged Population Surveillance Pregnancy Pregnancy Complications / chemically induced*, epidemiology, urine Pregnancy Trimester, Third Prevalence Residence Characteristics / statistics & numerical data Risk Factors Rural Health / statistics & numerical data Socioeconomic Factors Urinalysis Water Pollutants, Chemical / adverse effects*, analysis, metabolism Water Supply / analysis, statistics & numerical data |
| Chemical | |
Reg. No./Substance:
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0/Water Pollutants, Chemical; 7440-38-2/Arsenic |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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