Document Detail

Arrhythmogenic right ventricular cardiomyopathy.
MedLine Citation:
PMID:  11738273     Owner:  NLM     Status:  MEDLINE    
Arrhythmogenic right ventricular (RV) cardiomyopathy (ARVC) is a cardiomyopathy characterized pathologically by fibrofatty replacement primarily of the RV and clinically by life-threatening ventricular arrhythmias in apparently healthy young people. The prevalence of the disease has been estimated at 1 in 5,000 individuals, although this estimate will likely increase as awareness of the condition increases among physicians. Arrhythmogenic RV cardiomyopathy is recognized as a cause of sudden death during athletic activity because of its association with ventricular arrhythmias that are provoked by exercise-induced catecholamine discharge. Diagnosis may be difficult because many of the electrocardiographic abnormalities mimic patterns seen in normal children, and the disease often involves only patchy areas of the RV. For this reason, international diagnostic criteria for ARVC were proposed by an expert consensus panel in 1996. Treatment is directed to preventing life-threatening cardiac arrhythmias with medications and the use of implantable defibrillators. This article will present in detail the etiology, clinical presentation, diagnosis and management of this condition.
C Gemayel; A Pelliccia; P D Thompson
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't; Review    
Journal Detail:
Title:  Journal of the American College of Cardiology     Volume:  38     ISSN:  0735-1097     ISO Abbreviation:  J. Am. Coll. Cardiol.     Publication Date:  2001 Dec 
Date Detail:
Created Date:  2001-12-12     Completed Date:  2002-01-02     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  8301365     Medline TA:  J Am Coll Cardiol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  1773-81     Citation Subset:  AIM; IM    
Hartford Hospital, Division of Cardiology, Hartford, Connecticut, USA.
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MeSH Terms
Anti-Arrhythmia Agents / therapeutic use
Arrhythmogenic Right Ventricular Dysplasia / diagnosis*,  pathology,  therapy
Defibrillators, Implantable
Diagnosis, Differential
Diagnostic Imaging
Electrocardiography / drug effects
Heart Ventricles / pathology
Reg. No./Substance:
0/Anti-Arrhythmia Agents

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