Document Detail

Arrhythmogenic right ventricular cardiomyopathy as lethal complication factor after cardiac surgery.
MedLine Citation:
PMID:  19784568     Owner:  NLM     Status:  MEDLINE    
In patients with arrhythmogenic right ventricular dysplasia (ARVD), the right ventricular myocardium histologically discloses atrophy paralleled by fibrofatty or fatty replacement. Apoptosis is believed to be a putative major pathogenetic mechanism. Altogether, our knowledge of genetics, etiology and pathophysiology of ARVD has increased impressively in the last few years, and effective genetic tests now principally would be possible. Nevertheless, due to often uncharacteristic or even lacking symptoms, clinical diagnosis may be very difficult and could not be made during lifetime of patient presented here, partly due to additional, independent cardiac problems. The question of an effective preoperative diagnostic regimen for cardiosurgical interventions remains and seems to be currently open.
Marc Irqsusi; Sebastian Vogt; Wilhelm Nimphius; Sabine Pankuweit; Marc Kalinowski; Peter J Barth; Roland Moll; Rainer Moosdorf
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Publication Detail:
Type:  Case Reports; Journal Article     Date:  2009-09-27
Journal Detail:
Title:  Herz     Volume:  34     ISSN:  1615-6692     ISO Abbreviation:  Herz     Publication Date:  2009 Sep 
Date Detail:
Created Date:  2009-09-28     Completed Date:  2009-12-09     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  7801231     Medline TA:  Herz     Country:  Germany    
Other Details:
Languages:  eng     Pagination:  485-8     Citation Subset:  IM    
Department of Cardiac and Thoracovascular Surgery, University Hospital Giessen and Marburg GmbH, Marburg, Germany.
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MeSH Terms
Arrhythmogenic Right Ventricular Dysplasia / diagnosis*,  etiology*,  prevention & control
Cardiac Surgical Procedures / adverse effects*
Fatal Outcome
Middle Aged

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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