Document Detail

Arousal components which differentiate the MWT from the MSLT.
MedLine Citation:
PMID:  11403529     Owner:  NLM     Status:  MEDLINE    
STUDY OBJECTIVES: The purpose of this study was to determine the relative contribution of the instruction to maintain wakefulness versus posture change as major components determining sleep latency in the MWT as compared to the MSLT. DESIGN AND SETTING: After adaptation, subjects spent 3 nights and the following days in the laboratory. On each day, Ss had eight sleep latency measurements including four sleep latency tests from two of the following conditions: Lay down and Sleep (MSLT); Lay down and stay Awake; Sit up and Sleep; Sit up and stay Awake (MWT); and sit in a chair in front of a Computer and stay awake. PARTICIPANTS: Participants were 14 young adult normal sleepers. INTERVENTIONS: NA. MEASUREMENT AND RESULTS: Significant differences in sleep latency were found for each condition with respect to all of the others except that the Computer condition did not differ from the Sit-Awake condition. Means for conditions were: Lay-Sleep -11.1 minutes; Sit-Sleep -17.7 minutes; Lay-Awake - 21.7 minutes; Sit-Awake - 29.0 minutes; Computer - 30.1 minutes. Correlations between conditions declined as subjects sat up. CONCLUSIONS: The MWT differs from the MSLT by taking advantage of the arousal system (motivation and posture) to maintain alertness (i.e., increase sleep latency). These arousal effects are additive. MSLT results may not always correlate well with MWT results because the MWT measures the combined effects of the sleep and arousal systems while the MSLT, in ideal situations, measures only sleepiness.
M H Bonnet; D L Arand
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Sleep     Volume:  24     ISSN:  0161-8105     ISO Abbreviation:  Sleep     Publication Date:  2001 Jun 
Date Detail:
Created Date:  2001-06-13     Completed Date:  2001-11-01     Revised Date:  2009-01-29    
Medline Journal Info:
Nlm Unique ID:  7809084     Medline TA:  Sleep     Country:  United States    
Other Details:
Languages:  eng     Pagination:  441-7     Citation Subset:  IM    
Dayton Department of Veterans Affairs Medical Center, Wright State University and Kettering Medical Center, Dayton, OH 45428, USA. Bonnet.Michael@DAYTON.VA.GOV
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MeSH Terms
Arousal / physiology*
Middle Aged
Sleep, REM / physiology*
Wakefulness / physiology*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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