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Armenin and Isoarmenin - Two Prenylated Coumarins from the Aerial Parts of Artemisia armeniaca.
MedLine Citation:
PMID:  22083921     Owner:  NLM     Status:  In-Data-Review    
Abstract/OtherAbstract:
The reversed-phase (RP) preparative HPLC analyses of the MeOH extract of the aerial parts of Artemisia armeniaca yielded four prenylated coumarins, 7-hydroxy-8-(4-hydroxy-3-methylbutoxy)coumarin (named armenin), 8-hydroxy-7-(4-hydroxy-3-methylbutoxy)coumarin (named isoarmenin), lacarol, and deoxylacarol, together with five other compounds, including three flavonoid glycosides, quercetin 3-O-β-D-glucopyranoside, rutin, and kaempferol 3-O-β-D-glucopyranoside, and chlorogenic acid, and tryptophan. (10E,12Z)-9-Hydroxyoctadeca-10,12-dienoic acid (β-dimorphecolic acid) was isolated from the CH(2) Cl(2) extract. Armenin and isoarmenin were new coumarins. Structures of all compounds were determined by spectroscopic means, including UV, MS, 1D- and 2D-NMR. The in vitro free-radical-scavenging property of the extracts and isolated compounds was evaluated by the 1,1-diphenyl-2-picrylhydrazyl (DPPH) assay.
Authors:
Mahdi Mojarrab; Abbas Delazar; Sadeighe Bamdad Moghadam; Hossein Nazemiyeh; Lutfun Nahar; Yashodharan Kumarasamy; Solmaz Asnaashari; Abbas Hadjiakhoondi; Satyajit Dey Sarker
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Chemistry & biodiversity     Volume:  8     ISSN:  1612-1880     ISO Abbreviation:  Chem. Biodivers.     Publication Date:  2011 Nov 
Date Detail:
Created Date:  2011-11-15     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101197449     Medline TA:  Chem Biodivers     Country:  Switzerland    
Other Details:
Languages:  eng     Pagination:  2097-103     Citation Subset:  IM    
Copyright Information:
Copyright © 2011 Verlag Helvetica Chimica Acta AG, Zürich.
Affiliation:
Drug Applied Research Center, Tabriz University of Medical Sciences, Tabriz, Iran; School of Pharmacy, Tabriz University of Medical Sciences, Tabriz, Iran.
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