Document Detail

Are women who are treated for hypothyroidism at risk for pregnancy complications?
MedLine Citation:
PMID:  16647887     Owner:  NLM     Status:  MEDLINE    
OBJECTIVE: The purpose of this study was to investigate the outcomes that are associated with pregnancy and treated hypothyroidism. STUDY DESIGN: This was a retrospective cohort study of all women who received prenatal care and were delivered at the University of California, San Francisco, between 1989 and 2001. All patients with hypothyroidism diagnosed before pregnancy or early in pregnancy were identified. Maternal, fetal, and obstetric outcomes were then collected and analyzed for women with hypothyroidism and compared with women without hypothyroidism. RESULTS: Among 20,499 deliveries, there were 419 women (2.1%) who were treated for hypothyroidism during the study period. Hypothyroidism was more common among women > or =35 years old, white women, and women without Medicaid insurance. Treated hypothyroidism was not associated with any increase in maternal, fetal, or neonatal complications. In addition, hypothyroidism did not affect mode of delivery. CONCLUSION: Compared with patients without hypothyroidism, patients with treated hypothyroidism are not at any increased risk for perinatal morbidity.
Tina O Tan; Yvonne W Cheng; Aaron B Caughey
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Publication Detail:
Type:  Journal Article; Research Support, N.I.H., Extramural     Date:  2006-04-21
Journal Detail:
Title:  American journal of obstetrics and gynecology     Volume:  194     ISSN:  1097-6868     ISO Abbreviation:  Am. J. Obstet. Gynecol.     Publication Date:  2006 May 
Date Detail:
Created Date:  2006-05-01     Completed Date:  2006-06-01     Revised Date:  2007-11-14    
Medline Journal Info:
Nlm Unique ID:  0370476     Medline TA:  Am J Obstet Gynecol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  e1-3     Citation Subset:  AIM; IM    
Division of Maternal-Fetal Medicine, Department of Obstetrics, Gynecology and Reproductive Sciences, University of California, San Francisco, CA 94143, USA.
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MeSH Terms
Age Distribution
Cohort Studies
Hypothyroidism / complications*,  drug therapy*,  epidemiology
Pregnancy Complications / etiology*
Retrospective Studies
Risk Assessment
Grant Support

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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