Document Detail


Are the wolffian anomalies in males the phenotype corresponding to the müllerian anomalies in females?
MedLine Citation:
PMID:  8465853     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The Wolffian and Müllerian ducts are embryologically closely related. This survey was aimed to determine whether, as has been suggested, Wolffian duct anomalies in males are the phenotype corresponding to Müllerian anomalies in females. This was done by analysis of the phenotype of the males in associations and syndromes in which Müllerian duct anomalies are frequent, and of the phenotype of the females in families in which anomalies of the Wolffian ducts are found. It appears that the only relation between the 2 types of defects seems to be a developmental one. In cases of early insult, anomalies are seen in males and females (e.g., in the association of renal agenesis with Müllerian or Wolffian defects). On the other hand, in all the other associations or syndromes, no relation was observed. This suggests that Wolffian anomalies in males are not the phenotype corresponding to Müllerian anomalies in females.
Authors:
J Zlotogora
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  American journal of medical genetics     Volume:  45     ISSN:  0148-7299     ISO Abbreviation:  Am. J. Med. Genet.     Publication Date:  1993 Feb 
Date Detail:
Created Date:  1993-05-06     Completed Date:  1993-05-06     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  7708900     Medline TA:  Am J Med Genet     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  468-70     Citation Subset:  IM    
Affiliation:
Department of Human Genetics, Hadassah Medical Center, Hebrew University, Jerusalem, Israel.
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MeSH Terms
Descriptor/Qualifier:
Female
Humans
Male
Mullerian Ducts / abnormalities*,  embryology
Phenotype
Wolffian Ducts / abnormalities*,  embryology

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