Document Detail


Are two better than one? Angiotensin-converting enzyme inhibitors plus angiotensin receptor blockers for reducing blood pressure and proteinuria in kidney disease.
MedLine Citation:
PMID:  18178792     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Angiotensin-converting enzyme inhibitors and angiotensin receptor blockers each reduce proteinuria and blood pressure. Several studies have compared the antiproteinuric and antihypertensive effects of combination therapy with angiotensin-converting enzyme inhibitors and angiotensin receptor blockers with those of therapy with either drug class alone. This article reviews those trials as well as evidence suggesting a mechanism for the benefits observed with combination therapy.
Authors:
Stuart L Linas
Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't; Review    
Journal Detail:
Title:  Clinical journal of the American Society of Nephrology : CJASN     Volume:  3 Suppl 1     ISSN:  1555-905X     ISO Abbreviation:  Clin J Am Soc Nephrol     Publication Date:  2008 Jan 
Date Detail:
Created Date:  2008-01-07     Completed Date:  2008-03-05     Revised Date:  2013-06-06    
Medline Journal Info:
Nlm Unique ID:  101271570     Medline TA:  Clin J Am Soc Nephrol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  S17-23     Citation Subset:  IM    
Affiliation:
Department of Internal Medicine, Division of Renal Diseases and Hypertension, University of Colorado Health Sciences Center, Denver, Colorado 80204, USA. stuart.linas@uchsc.edu
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MeSH Terms
Descriptor/Qualifier:
Angiotensin II Type 1 Receptor Blockers / adverse effects,  therapeutic use*
Angiotensin-Converting Enzyme Inhibitors / adverse effects,  therapeutic use*
Drug Therapy, Combination
Humans
Hypertension / complications,  drug therapy*
Kidney Diseases / complications*
Proteinuria / drug therapy*,  etiology
Chemical
Reg. No./Substance:
0/Angiotensin II Type 1 Receptor Blockers; 0/Angiotensin-Converting Enzyme Inhibitors
Comments/Corrections

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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