| Are there any differences in colorectal cancer between young and elderly patients? | |
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MedLine Citation:
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PMID: 15655603 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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BACKGROUND: There is a controversy as to whether colorectal cancer (CRC) in the young population is more aggressive than in the elderly population, and hence has a less favourable prognosis. The aim of this study is to review the results of treatment of young and elderly patients diagnosed with CRC during a 10-year period (1994-2003). METHODS: We studied two distinct age groups: young (aged under 40) and elderly (aged over 80), who underwent surgery in the 1st Surgical Department. The young consisted of 11 patients with ages ranging from 37 to 40 (average age 39). The elderly consisted of 45 patients with ages ranging from 81 to 91 (average age 86). We compared clinical signs, pathological grade, Dukes' stage and presence of metastasis, average hospitalisation time, and postoperative mortality. RESULTS: The results of patients admitted to hospital with a diagnosis of acute abdomen were 9% in the young and 7% of the elderly. Those in stage C in Dukes' classification were 54.5% in the young group, and 44.4% in the elderly group. Those with undifferentiated adenocarcinoma were 36.3% in the young, and 8.8% in the elderly. During surgery, distal metastases were found in 18% of the young and 24.4% of the elderly. The average hospitalisation time of young and elderly patients was 13 and 15.2 days, respectively. The postoperative mortality rates of the young and elderly patients were 0% and 4%, respectively. CONCLUSIONS: Except for a higher rate of undifferentiated adenocarcinoma in young patients, there were no particular differences in the compared factors between the two age groups. The mortality rates do not indicate a less favourable prognosis for the young. |
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Authors:
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H Frizis; A Papadopoulos; G Akritidis; H-R Frizis; G Hatzitheoharis |
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Publication Detail:
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Type: Comparative Study; Journal Article |
Journal Detail:
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Title: Techniques in coloproctology Volume: 8 Suppl 1 ISSN: 1123-6337 ISO Abbreviation: Tech Coloproctol Publication Date: 2004 Nov |
Date Detail:
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Created Date: 2005-01-18 Completed Date: 2005-02-23 Revised Date: 2006-11-15 |
Medline Journal Info:
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Nlm Unique ID: 9613614 Medline TA: Tech Coloproctol Country: Italy |
Other Details:
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Languages: eng Pagination: s147-8 Citation Subset: IM |
Affiliation:
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1st Surgical Department, Ippocration General Hospital, Thessaloniki, Greece. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adenocarcinoma
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mortality*,
pathology*,
surgery Adult Age Distribution Aged Aged, 80 and over Biopsy, Needle Cohort Studies Colectomy / methods Colorectal Neoplasms / mortality*, pathology*, surgery Disease-Free Survival Female Humans Immunohistochemistry Incidence Male Middle Aged Neoplasm Staging Prognosis Retrospective Studies Risk Assessment Sensitivity and Specificity Sex Distribution Survival Analysis |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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