Document Detail


Are stereotactic sample biopsies still of value in the modern management of pineal region tumours? Lessons from a single-department, retrospective series.
MedLine Citation:
PMID:  21331478     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
OBJECTIVE: Recent improvements in imaging-based diagnosis, the broader application of neuroendoscopic techniques and advances in open surgery techniques mean that the need for stereotactic biopsies in the management of pineal region tumours must be reevaluated. The primary aim of this retrospective study was to establish whether stereotactic biopsy is still of value in the modern management of pineal region tumours. METHODS: From 1985 to 2009, 88 consecutive patients underwent a stereotactic biopsy in our institution (51 males and 37 females; median age at presentation 30; range 2-74). RESULTS: Accurate tissue diagnoses were obtained in all but one case (i.e. 99%). In one case (1%), three distinct stereotactic procedures were necessary to obtain a tissue diagnosis. There was no mortality or permanent morbidity associated with stereotactic biopsy. One patient (1%) presented an intra-parenchymal hematoma but no related clinical symptoms. Five patients (6%) presented transient morbidity, which lasted for between 2 days and 3 weeks after the biopsy. CONCLUSIONS: To guide subsequent treatment, we believe that histological diagnosis is paramount. Stereotactic biopsies are currently the safest and the most efficient way of obtaining this essential information. Recent improvements in stereotactic technology (particularly robotic techniques) appear to be very valuable, with almost no permanent morbidity or mortality risk and no decrease in the accuracy rate. In our opinion, other available neurosurgical techniques (such as endoscopic neurosurgery, stereotactic neurosurgery and open microsurgery) are complementary and not competitive.
Authors:
Michel Lefranc; Gustavo Touzet; Sabine Caron; Claude Alain Maurage; Richard Assaker; Serge Blond
Related Documents :
21899588 - Agminated cellular neurothekeoma.
7856728 - The bcl-2 proto-oncogene and the gastrointestinal epithelial tumor progression model.
1523938 - Identification of blastocystis hominis by colonic brush cytology. a case report.
21345688 - Unrecognized hemangiopericytoma of posterior cervical region with intracranial extension.
20818808 - Endoscopic ultrasound in chronic pancreatitis: where are we now?
9914938 - Large synovial cyst of the pelvis containing rice bodies. a case report.
Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2011-2-18
Journal Detail:
Title:  Acta neurochirurgica     Volume:  -     ISSN:  0942-0940     ISO Abbreviation:  -     Publication Date:  2011 Feb 
Date Detail:
Created Date:  2011-2-18     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0151000     Medline TA:  Acta Neurochir (Wien)     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Affiliation:
Department of Neurosurgery, CHR&U Hôpital Roger Salengro, rue du Professeur Emile Laine, 59037, Lille, France, lefrancm@gmail.com.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  The impact of subdural air collection on intraoperative motor and somatosensory evoked potentials: f...
Next Document:  An epidemiologic and clinical overview of medical and psychopathological comorbidities in major psyc...