Document Detail

Are probiotics safe for use during pregnancy and lactation?
MedLine Citation:
PMID:  21402964     Owner:  NLM     Status:  MEDLINE    
QUESTION: There has been a great deal of discussion in both the medical and lay literature about the use of probiotics to improve general health. Subsequently, pregnant women have been asking me if probiotics used for treating conditions such as bacterial vaginosis and diarrhea are safe to use during pregnancy and lactation.
ANSWER: Current data suggest that probiotic supplementation is rarely systemically absorbed when used by healthy individuals. One meta-analysis and several randomized controlled trials conducted with women during the third trimester of pregnancy did not report an increase in adverse fetal outcomes. There have been no published studies addressing Saccharomyces species use in pregnancy. Probiotics are unlikely to be transferred into breast milk.
Jackie Elias; Pina Bozzo; Adrienne Einarson
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Canadian family physician Médecin de famille canadien     Volume:  57     ISSN:  1715-5258     ISO Abbreviation:  Can Fam Physician     Publication Date:  2011 Mar 
Date Detail:
Created Date:  2011-03-15     Completed Date:  2011-08-01     Revised Date:  2013-06-30    
Medline Journal Info:
Nlm Unique ID:  0120300     Medline TA:  Can Fam Physician     Country:  Canada    
Other Details:
Languages:  eng     Pagination:  299-301     Citation Subset:  IM    
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MeSH Terms
Breast Feeding
Consumer Product Safety*
Diarrhea / therapy
Probiotics / adverse effects,  therapeutic use*
Vaginosis, Bacterial / therapy

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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