Document Detail

Are preoperative serum calcium, parathyroid hormone, and adenoma weight predictive of postoperative hypocalcemia?
MedLine Citation:
PMID:  12516813     Owner:  NLM     Status:  MEDLINE    
The objective of this study is to determine whether preoperative serum calcium, parathyroid hormone, or adenoma weight is predictive of postoperative hypocalcemia after removal of a parathyroid adenoma. A retrospective chart review was performed for consecutive parathyroidectomy patients over a 6-year period at a community-based teaching institution. Patients with renal failure (serum creatinine >1.7), hyperplastic disease, and parathyroid carcinoma were excluded. The outcome measures were postoperative serum calcium and the presence of signs or symptoms such as paresthesias, anxiety, or Chvostek's sign. One hundred forty-one patients underwent parathyroidectomy during the study period. Fifty-four patients were excluded as a result of hyperplastic disease, renal failure, carcinoma, or unavailable records. Of the remaining 87 patients 25 (28.7%) developed hypocalcemia (serum calcium < 8.0), and ten patients (11.5%), developed symptoms. The mean preoperative calcium levels for the normocalcemic and hypocalcemic groups were 10.9 and 10.6, respectively (P < 0.217). The mean preoperative parathyroid hormone levels (normal 10-54) were 214 and 139, respectively (P < 0.305), and the mean adenoma weights were 1.059 and 1.337 g respectively (P < 0.343). This study demonstrates no statistically significant difference in the mean preoperative serum calcium levels, parathyroid hormone levels, or adenoma weight between normocalcemic and hypocalcemic patients postoperatively.
Pamela L Strickland; James Recabaren
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  The American surgeon     Volume:  68     ISSN:  0003-1348     ISO Abbreviation:  Am Surg     Publication Date:  2002 Dec 
Date Detail:
Created Date:  2003-01-08     Completed Date:  2003-01-29     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0370522     Medline TA:  Am Surg     Country:  United States    
Other Details:
Languages:  eng     Pagination:  1080-2     Citation Subset:  IM    
Department of Surgery, Huntington Memorial Hospital, Pasadena, California, USA.
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MeSH Terms
Adenoma / blood,  pathology*,  surgery
Calcium / blood*
Hypocalcemia / blood,  etiology*
Medical Records
Middle Aged
Organ Size
Parathyroid Hormone / blood*
Parathyroid Neoplasms / blood,  pathology*,  surgery
Parathyroidectomy / adverse effects*
Predictive Value of Tests
Preoperative Care
Retrospective Studies
Reg. No./Substance:
0/Parathyroid Hormone; 7440-70-2/Calcium

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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