| Are preoperative serum calcium, parathyroid hormone, and adenoma weight predictive of postoperative hypocalcemia? | |
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MedLine Citation:
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PMID: 12516813 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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The objective of this study is to determine whether preoperative serum calcium, parathyroid hormone, or adenoma weight is predictive of postoperative hypocalcemia after removal of a parathyroid adenoma. A retrospective chart review was performed for consecutive parathyroidectomy patients over a 6-year period at a community-based teaching institution. Patients with renal failure (serum creatinine >1.7), hyperplastic disease, and parathyroid carcinoma were excluded. The outcome measures were postoperative serum calcium and the presence of signs or symptoms such as paresthesias, anxiety, or Chvostek's sign. One hundred forty-one patients underwent parathyroidectomy during the study period. Fifty-four patients were excluded as a result of hyperplastic disease, renal failure, carcinoma, or unavailable records. Of the remaining 87 patients 25 (28.7%) developed hypocalcemia (serum calcium < 8.0), and ten patients (11.5%), developed symptoms. The mean preoperative calcium levels for the normocalcemic and hypocalcemic groups were 10.9 and 10.6, respectively (P < 0.217). The mean preoperative parathyroid hormone levels (normal 10-54) were 214 and 139, respectively (P < 0.305), and the mean adenoma weights were 1.059 and 1.337 g respectively (P < 0.343). This study demonstrates no statistically significant difference in the mean preoperative serum calcium levels, parathyroid hormone levels, or adenoma weight between normocalcemic and hypocalcemic patients postoperatively. |
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Authors:
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Pamela L Strickland; James Recabaren |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: The American surgeon Volume: 68 ISSN: 0003-1348 ISO Abbreviation: Am Surg Publication Date: 2002 Dec |
Date Detail:
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Created Date: 2003-01-08 Completed Date: 2003-01-29 Revised Date: 2004-11-17 |
Medline Journal Info:
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Nlm Unique ID: 0370522 Medline TA: Am Surg Country: United States |
Other Details:
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Languages: eng Pagination: 1080-2 Citation Subset: IM |
Affiliation:
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Department of Surgery, Huntington Memorial Hospital, Pasadena, California, USA. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adenoma
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blood,
pathology*,
surgery Calcium / blood* Female Humans Hypocalcemia / blood, etiology* Male Medical Records Middle Aged Organ Size Parathyroid Hormone / blood* Parathyroid Neoplasms / blood, pathology*, surgery Parathyroidectomy / adverse effects* Predictive Value of Tests Preoperative Care Retrospective Studies |
| Chemical | |
Reg. No./Substance:
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0/Parathyroid Hormone; 7440-70-2/Calcium |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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