Document Detail

Are prenatal, obstetric, and infant complications associated with postpartum psychosis among women with pre-conception psychiatric hospitalisations?
MedLine Citation:
PMID:  23194279     Owner:  NLM     Status:  MEDLINE    
OBJECTIVE: To examine the associations of maternal and infant complications with postpartum hospitalisation for psychosis in women with a pre-conception history of psychiatric hospitalisation.
DESIGN: Population-based study.
SETTING: Swedish medical birth register.
POPULATION: Primiparous women who gave birth between 1 January 1987 and 31 December 2001, and who had a pre-conception history of psychiatric hospitalisation but who were not hospitalised during pregnancy (n = 1842).
METHODS: International Classification of Diseases (ICD) codes were used to identify prenatal, obstetric, postpartum maternal complications, and newborn health conditions. We used multivariable logistic regression to describe the associations between maternal and infant health conditions and the odds for postpartum hospitalisation for psychosis.
MAIN OUTCOME MEASURE: Psychiatric hospitalisation within 90 days of delivery.
RESULTS: Compared with women who did not have a postpartum psychiatric hospitalisation, hospitalised women were at 2.3 times higher odds (95% CI 1.0-4.9) of having non-psychiatric puerperium complications (e.g. infection, lactation problems or venous complications). No other maternal complications were associated with postpartum psychiatric hospitalisation. Although their infants were at no higher odds for health complications, the offspring of women who had a postpartum psychiatric hospitalisation were at 4.1 times higher odds (95% CI 1.3-12.6) of death within the first 365 days of life than those of women who were not hospitalised.
CONCLUSIONS: We found no prenatal indicators of postpartum risk for psychiatric hospitalisation among high-risk women, but they had higher odds of postpartum pregnancy-related medical problems and, rarely, offspring death.
W L Hellerstedt; S M Phelan; S Cnattingius; C M Hultman; B L Harlow
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Publication Detail:
Type:  Comparative Study; Journal Article; Research Support, Non-U.S. Gov't     Date:  2012-11-30
Journal Detail:
Title:  BJOG : an international journal of obstetrics and gynaecology     Volume:  120     ISSN:  1471-0528     ISO Abbreviation:  BJOG     Publication Date:  2013 Mar 
Date Detail:
Created Date:  2013-02-12     Completed Date:  2013-04-04     Revised Date:  2014-05-08    
Medline Journal Info:
Nlm Unique ID:  100935741     Medline TA:  BJOG     Country:  England    
Other Details:
Languages:  eng     Pagination:  446-55     Citation Subset:  AIM; IM    
Copyright Information:
© 2012 The Authors BJOG An International Journal of Obstetrics and Gynaecology © 2012 RCOG.
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MeSH Terms
Bipolar Disorder / complications*,  epidemiology
Congenital Abnormalities / epidemiology
Hospitalization / statistics & numerical data
Infant, Low Birth Weight
Infant, Newborn
Preconception Care / statistics & numerical data
Premature Birth / epidemiology,  psychology
Psychotic Disorders / complications*,  epidemiology
Puerperal Disorders / epidemiology,  psychology*
Risk Factors
Sweden / epidemiology
Young Adult
Grant Support

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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