Document Detail

Are patients better than the laboratory in assessing sweating? Validation study.
MedLine Citation:
PMID:  16416613     Owner:  NLM     Status:  MEDLINE    
BACKGROUND: Primary focal hyperhidrosis is a hereditary condition characterized by excessive sweating affecting a variety of areas, including the palms. In most cases, the decision to treat a patient is based only on the patient's own description of the symptoms because laboratory tests have not been established in clinical practice. OBJECTIVE: To validate a subjective self-assessment scale for sweating in comparison with an objective method of quantifying evaporation from the skin surface. METHODS: We studied palmar sweating in 20 patients with primary focal hyperhidrosis and 20 age- and gender-matched controls. Four times in each subject, we obtained measurements of the evaporation in palms and the self-evaluation scale (SES) scores on a proportional scale from 0 (no sweating) to 10 (worst imaginable sweating). RESULTS: Good correlation was found between the SES score and evaporation assessment (R = .65). The SES score was easier to obtain and provided better diagnostic sensitivity and specificity. They leveled out at over 80% when a score of 3 was used as the threshold level; for evaporimetry, sensitivity equalled specificity at 70% at the threshold 90 mg -2h(-1). CONCLUSION: We confirm the usefulness of the SES in assessing palmar sweating and discuss the current restrictions in its use in clinical diagnosis. We propose that the scale can be added effortlessly to research or clinical protocols to provide the necessary validation in wider spectra of patients.
Anne-Lene Krogstad; Stefan Kazimierz Piechnik
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't; Validation Studies    
Journal Detail:
Title:  Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.]     Volume:  31     ISSN:  1076-0512     ISO Abbreviation:  Dermatol Surg     Publication Date:  2005 Nov 
Date Detail:
Created Date:  2006-01-18     Completed Date:  2006-02-23     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  9504371     Medline TA:  Dermatol Surg     Country:  United States    
Other Details:
Languages:  eng     Pagination:  1434-9     Citation Subset:  IM    
Institute of Clinical Neuroscience, Göteborg University, Göteborg, Sweden.
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MeSH Terms
Hyperhidrosis / diagnosis*,  physiopathology
Patient Participation*
ROC Curve
Sensitivity and Specificity
Severity of Illness Index

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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