Document Detail


Are patient characteristics helpful in recognizing mild COPD (GOLD I) in daily practice?
MedLine Citation:
PMID:  17118864     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
OBJECTIVE: To determine whether in a high-risk group of middle-aged male current smokers, patient characteristics are useful to recognize mild COPD (GOLD stage I). DESIGN: In a cross-sectional study spirometry was performed according to the American Thoracic Society criteria. COPD was defined according to the GOLD criteria for COPD. SETTING: Primary care. SUBJECTS: Male smokers, aged 40-65 years, without documented lung disease in the population at large. MAIN OUTCOME MEASURES: Medical records were scrutinized to collect patient characteristics. Multiple logistic regression analysis was used to identify independent determinants of mild COPD. RESULTS: A total of 567 subjects participated. COPD, defined by a FEV1/FVC ratio < 0.7, was detected in 170 subjects (30.0%, 95% CI 26.2-33.9%). In 149 subjects (26.3%; 22.7-30.1%) COPD was mild (GOLD stage I) and in 21 subjects (3.7%; 2.3-5.6%) moderate (GOLD stage II). Only age and cough were independently associated with the presence of mild COPD. The ability of these determinants to discriminate between subjects with or without mild COPD was relatively poor (ROC area 0.65). Therefore no prediction rule was developed. CONCLUSION: Our results indicate that patient characteristics are not helpful to recognize mild COPD (GOLD stage I) in middle-aged male smokers.
Authors:
Roeland M M Geijer; Alfred P E Sachs; Theo J M Verheij; Jan-Willem J Lammers; Philippe L Salomé; Arno W Hoes
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Scandinavian journal of primary health care     Volume:  24     ISSN:  0281-3432     ISO Abbreviation:  Scand J Prim Health Care     Publication Date:  2006 Dec 
Date Detail:
Created Date:  2006-11-22     Completed Date:  2007-01-10     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8510679     Medline TA:  Scand J Prim Health Care     Country:  Norway    
Other Details:
Languages:  eng     Pagination:  237-42     Citation Subset:  IM    
Affiliation:
Julius Centre for Health Sciences and Primary Care, University Medical Centre Utrecht, The Netherlands. rmmgeyer@hotmail.com
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MeSH Terms
Descriptor/Qualifier:
Adult
Cross-Sectional Studies
Family Practice
Forced Expiratory Volume
Humans
Male
Middle Aged
Predictive Value of Tests
Pulmonary Disease, Chronic Obstructive / diagnosis*,  etiology,  physiopathology
Questionnaires
Severity of Illness Index
Smoking / adverse effects
Spirometry

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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