Document Detail


Are oppositional-defiant and hyperactive-inattentive symptoms developmental precursors to conduct problems in late childhood?: genetic and environmental links.
MedLine Citation:
PMID:  18648930     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Inattentive-hyperactive and oppositional behavior have been hypothesized to be developmental precursors to conduct problems. We tested these hypotheses using a longitudinal sample of 6,466 offspring of women selected from nationally representative US households. Conduct problems across 8-13 years were robustly predicted by conduct problems at 4-7 years, but also were independently predicted to a small extent by both inattentive-hyperactive and oppositional behaviors at 4-7 years. Longitudinal multivariate behavior genetic analyses revealed that the genetic and environmental factors that influence conduct problems at both 4-7 and 8-13 years also influence the putative precursors at 4-7 years. After genetic and environmental influences on conduct problems at 4-7 years were taken into account, however, inattentive-hyperactive and oppositional behavior at 4-7 years shared causal influences with conduct problems 8-13 years to a negligible extent. These findings suggest that after early conduct problems are controlled, little is gained in terms of prediction or understanding genetic and environmental influences on later child conduct problems by treating early inattentive-hyperactive and oppositional behavior as developmental precursors to later conduct problems.
Authors:
Benjamin B Lahey; Carol A Van Hulle; Paul J Rathouz; Joseph Lee Rodgers; Brian M D'Onofrio; Irwin D Waldman
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Journal of abnormal child psychology     Volume:  37     ISSN:  1573-2835     ISO Abbreviation:  J Abnorm Child Psychol     Publication Date:  2009 Jan 
Date Detail:
Created Date:  2009-01-22     Completed Date:  2009-07-13     Revised Date:  2010-09-13    
Medline Journal Info:
Nlm Unique ID:  0364547     Medline TA:  J Abnorm Child Psychol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  45-58     Citation Subset:  IM    
Affiliation:
Department of Health Studies, University of Chicago, Chicago, IL 60637, USA. blahey@uchicago.edu
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MeSH Terms
Descriptor/Qualifier:
Adolescent
Attention Deficit Disorder with Hyperactivity / diagnosis,  epidemiology*,  genetics*
Attention Deficit and Disruptive Behavior Disorders / diagnosis,  epidemiology*,  genetics*
Child
Child, Preschool
Conduct Disorder / diagnosis,  epidemiology*,  genetics*
Female
Genotype*
Humans
Male
Prospective Studies
Social Environment*
Grant Support
ID/Acronym/Agency:
R01 MH070025-04/MH/NIMH NIH HHS

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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