Document Detail


Are most secondary acute lymphoblastic leukemias mixed acute leukemias?
MedLine Citation:
PMID:  2915919     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
A case of acute lymphoblastic leukemia (ALL) secondary to X-ray exposure is reported. The lymphoblasts expressed T-cell and myelomonocytic differentiation-related surface antigens. Clonal chromosomal abnormalities including t(2;12)(q25;q13),-10,der(10), del(11)(q14),der(12) and r were observed. A review of the cytogenetic data suggests that most secondary ALLs, with the exception of Burkitt type ALLs, may be biphenotypic or mixed acute leukemias.
Authors:
S J Chen; Z Chen; J Derré; M Le Coniat; F Valensi; F Sigaux; R Berger
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Nouvelle revue française d'hématologie     Volume:  31     ISSN:  -     ISO Abbreviation:  Nouv Rev Fr Hematol     Publication Date:  1989  
Date Detail:
Created Date:  1989-03-23     Completed Date:  1989-03-23     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  7909092     Medline TA:  Nouv Rev Fr Hematol     Country:  GERMANY, WEST    
Other Details:
Languages:  eng     Pagination:  17-22     Citation Subset:  IM    
Affiliation:
Unité INSERM U 301, CNRS, Paris, France.
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MeSH Terms
Descriptor/Qualifier:
Adult
Antigens, Differentiation / analysis
Female
Gene Rearrangement
Histocompatibility Testing
Humans
Karyotyping
Leukemia, Biphenotypic, Acute / etiology*,  genetics
Leukemia, Radiation-Induced / classification*,  genetics
Phenotype
Precursor Cell Lymphoblastic Leukemia-Lymphoma / classification*,  etiology,  genetics
Tumor Markers, Biological / analysis
Chemical
Reg. No./Substance:
0/Antigens, Differentiation; 0/Tumor Markers, Biological

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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