Document Detail

Are the laboratory and field conditions observations of acute mountain sickness related?
MedLine Citation:
PMID:  9327114     Owner:  NLM     Status:  MEDLINE    
In order to study relationships between acute mountain sickness (AMS) observations done both during a short-term hypoxic exposure in a hypobaric chamber, and in field conditions during a high altitude expedition, nine subjects were submitted to a 9-h hypoxic exposure in a hypobaric chamber. Then, they experienced a high altitude expedition in the Himalayas. The Lake Louise AMS scoring system was used to assess AMS in both conditions, especially the self report questionnaire. During the expedition, the mean self report score of each subject, defined as the ratio between the sum of daily self report scores and the duration of the expedition, appears to be correlated not only to the maximal self report score observed in altitude (r = +0.77, p < 0.05) but also to the self report and self report+clinical assessment scores observed at the end of the hypobaric chamber sojourn (r = +0.81, p < 0.01 and r = +0.75, p < 0.05, respectively). In conclusion, the Lake Louise AMS scoring system, especially the self report questionnaire, is relevant to assess AMS with simplicity and rapidity both in laboratory and in field conditions. Our study also suggests that AMS induced by a short term sojourn in a hypobaric chamber is related to AMS observed in field conditions.
G Savourey; A Guinet; Y Besnard; N Garcia; A Hanniquet; J Bittel
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Publication Detail:
Type:  Comparative Study; Journal Article    
Journal Detail:
Title:  Aviation, space, and environmental medicine     Volume:  68     ISSN:  0095-6562     ISO Abbreviation:  Aviat Space Environ Med     Publication Date:  1997 Oct 
Date Detail:
Created Date:  1997-11-06     Completed Date:  1997-11-06     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  7501714     Medline TA:  Aviat Space Environ Med     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  895-9     Citation Subset:  IM; S    
Unité de Thermophysiologie, Centre de Recherches du Service de Santé des Armées, La Tronche, France.
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MeSH Terms
Acute Disease
Altitude Sickness / diagnosis,  physiopathology*,  psychology
Questionnaires / standards*
Reproducibility of Results
Severity of Illness Index*
Time Factors

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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