Document Detail

Are intraventricular gradients a cause of false positive treadmill exercise tests?
MedLine Citation:
PMID:  22682689     Owner:  NLM     Status:  Publisher    
BACKGROUND: Treadmill exercise testing has low specificity for the detection of significant epicardial coronary artery disease (CAD). A possible mechanism to explain some of the false positives is transient subendocardial ischemia induced by intraventricular gradients (IVG) during stress. The development of IVG during dobutamine stress echocardiography (DSE) occurs in 8-38% of non-selected populations. OBJECTIVES: To determine: METHODS AND RESULTS: We evaluated 50 consecutive patients with false positive treadmill stress tests (normal CT coronary angiography, nuclear perfusion tests or angiography) with DSE (2D and Doppler evaluation). All DSE exams were negative for ischemia. Stress-induced IVG was seen in 34 of the 50 patients (68%) and 16 patients (32%) did not develop IVG (p<0.05). The prevalence of IVG in our selected population (68%) was significantly higher than that described for non-selected populations (8-38%) (p<0.001). Most patient characteristics (gender, age, risk factors for CAD, treatment with beta-blockers/calcium antagonists, significant valvular disease/left ventricular hypertrophy [LVH], symptoms, and blood pressure during stress) were not statistically associated with the prevalence of IVG (p>0.05). However, the presence of IVG was associated with the occurrence of ischemic ST depression during dobutamine stress echo (p<0.05). CONCLUSIONS:
Nuno Cardim; Pedro Campos; Daniel Ferreira; Vanda Carmelo; Júlia Toste; Marisa Trabulo; Teresa Santos; Sylvie da Mariana; Francisco Pereira Machado; José Roquette
Related Documents :
16819629 - Exercise interest and preferences among patients diagnosed with primary brain cancer.
25051209 - Functional performance of female patients more than 6 months after total hip arthroplas...
2911619 - Exercise programs for patients with post-polio syndrome: a case report.
22682689 - Are intraventricular gradients a cause of false positive treadmill exercise tests?
16305269 - Physical therapy treatment effectiveness for osteoarthritis of the knee: a randomized c...
12441569 - The effect of education on backpack wearing and posture in a middle school population.
3084449 - Low acute hypoxic ventilatory response and hypoxic depression in acute altitude sickness.
25378959 - People who perceive themselves as active cannot identify the intensity recommended by t...
21439969 - Exercise-induced expression of cardiac atp-sensitive potassium channels promotes action...
Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2012-6-8
Journal Detail:
Title:  Revista portuguesa de cardiologia : orgao oficial da Sociedade Portuguesa de Cardiologia = Portuguese journal of cardiology : an official journal of the Portuguese Society of Cardiology     Volume:  -     ISSN:  0870-2551     ISO Abbreviation:  -     Publication Date:  2012 Jun 
Date Detail:
Created Date:  2012-6-11     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8710716     Medline TA:  Rev Port Cardiol     Country:  -    
Other Details:
Languages:  ENG; POR     Pagination:  -     Citation Subset:  -    
Copyright Information:
Copyright © 2011 Sociedade Portuguesa de Cardiologia. Published by Elsevier España. All rights reserved.
Cardiology Department, Hospital da Luz, Lisbon, Portugal.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  Influence of inclusion of chestnut in the finishing diet on fatty acid profile of dry-cured ham from...
Next Document:  Cardiac thrombus and conduction disorder in takotsubo cardiomyopathy.