Document Detail


Are hypertrophic astrocytes a sufficient criterion of perinatal telencephalic leucoencephalopathy?
MedLine Citation:
PMID:  4714100     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
To determine if the presence of amphophilic globules (GL) in infant cerebral white matter was a necessary criterion of perinatal telencephalic leucoencephalopathy (PTL), the epidemiological features of infants who had PTL-that is, hypertrophic astrocytes and amphophilic globules (HA·GL)-in their cerebral white matter were compared with those of infants who had hypertrophic astrocytes, but who did not have amphophilic globules (HA·[unk]). Postmortem bacteraemia was seen much more frequently in infants with HA·GL than in infants with HA·[unk] (P<0·05). In addition, infants with HA·GL tended to die at older postnatal ages than infants with HA·[unk]. These observations are in keeping with the view that HA·GL and HA·[unk] are not epidemiologically identical. The operational definition of PTL therefore remains the occurrence of both HA and GL in infant cerebral white matter.
Authors:
A Leviton; F H Gilles
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Journal of neurology, neurosurgery, and psychiatry     Volume:  36     ISSN:  0022-3050     ISO Abbreviation:  J. Neurol. Neurosurg. Psychiatr.     Publication Date:  1973 Jun 
Date Detail:
Created Date:  1973-08-28     Completed Date:  1973-08-28     Revised Date:  2012-05-30    
Medline Journal Info:
Nlm Unique ID:  2985191R     Medline TA:  J Neurol Neurosurg Psychiatry     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  383-8     Citation Subset:  IM    
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MeSH Terms
Descriptor/Qualifier:
Age Factors
Autopsy
Cerebral Cortex / pathology*
Epidemiologic Methods
Female
Humans
Hypertrophy
Infant
Infant, Newborn
Infant, Newborn, Diseases*
Leukoencephalopathy, Progressive Multifocal / complications,  etiology,  pathology*
Male
Neuroglia*
Sepsis / etiology
Telencephalon / pathology*
Comments/Corrections

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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