Document Detail

Are home ventilators able to guarantee a minimal tidal volume?
MedLine Citation:
PMID:  20217049     Owner:  NLM     Status:  MEDLINE    
OBJECTIVE: The aim of the study was to evaluate the ability of home ventilators to maintain a minimal tidal volume during different conditions associated with alveolar hypoventilation. DESIGN: Bench evaluation coupled with an in vivo study on two healthy subjects. SETTING: Tertiary university hospital and research unit. INTERVENTIONS: Six ventilators having a "volume guarantee" module (Synchrony II, Philips Respironics; Vivo 40, Breas; Legendair, Airox; Elisee 150, Philips Respironics; Ventimotion, Weinmann; and VS III, Resmed) were tested on a lung bench in a baseline condition and in three conditions associated with alveolar hypoventilation: increase in airway resistance, decrease in lung compliance, and non-intentional leaks. An in vivo study completed the bench study for the non-intentional leak condition. MEASUREMENTS AND RESULTS: The six ventilators were able to maintain a minimal tidal volume during an increase in airway resistance and a decrease in lung compliance. The maintenance of a minimal tidal volume during a non-intentional leak was more difficult and was associated with large variations in tidal volume, a default of pressure support delivery for some devices, and patient-ventilator dyssynchrony, both during the bench and the in vivo study. CONCLUSIONS: The six home ventilators tested in the study were able to maintain a minimal tidal volume during an increase in airway resistance and a decrease in lung compliance, but not during a non-intentional leak.
Brigitte Fauroux; Karl Leroux; Jean-Louis Pépin; Frédéric Lofaso; Bruno Louis
Related Documents :
17320009 - Impact of a pressure-responsive flow-limiting valve on bag-valve-mask ventilation in an...
19184209 - Pressure-controlled versus volume-controlled ventilation during one-lung ventilation in...
1542839 - Pnemostasis of injured lung in rabbits with gelatin-resorcinol formaldehyde-glutaraldeh...
1758739 - Inspiratory time and pulmonary function in mechanically ventilated babies with chronic ...
1931409 - Delayed pneumothorax after subclavian vein catheterization and positive pressure ventil...
11179109 - Dynamic behavior during noninvasive ventilation: chaotic support?
7877319 - Effect of vancomycin infusion on cardiac function in patients scheduled for cardiac ope...
18250979 - A comparison of nicardipine and labetalol for acute hypertension management following s...
3005169 - Renal and endocrine response to saline infusion in essential hypertension.
Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't     Date:  2010-03-09
Journal Detail:
Title:  Intensive care medicine     Volume:  36     ISSN:  1432-1238     ISO Abbreviation:  Intensive Care Med     Publication Date:  2010 Jun 
Date Detail:
Created Date:  2010-05-06     Completed Date:  2010-09-08     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  7704851     Medline TA:  Intensive Care Med     Country:  United States    
Other Details:
Languages:  eng     Pagination:  1008-14     Citation Subset:  IM    
Pediatric Pulmonary Department, Research Unit, National Reference Center for Rare Lung Diseases, INSERM, UMR S-938, AP-HP, Hôpital Armand-Trousseau, Université Pierre et Marie Curie-Paris 6, 75012, Paris, France.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Airway Resistance / physiology
Equipment Failure Analysis*
Home Care Services*
Lung Compliance / physiology
Positive-Pressure Respiration / instrumentation*
Respiratory Function Tests
Sleep Apnea, Central / therapy
Tidal Volume / physiology*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  A critical appraisal of the quality of critical care pharmacotherapy clinical practice guidelines an...
Next Document:  Effects of varenicline and mecamylamine on the acquisition, expression, and reinstatement of nicotin...