Document Detail

Are MIBI/tetrofosmin heart studies a potential radiation hazard to technologists?
MedLine Citation:
PMID:  9259531     Owner:  NLM     Status:  MEDLINE    
The number of nuclear medicine studies is increasing and they are becoming more complex and time-consuming. In particular, this is true of myocardial perfusion investigations. We use a one-day protocol for these studies, utilizing 99Tc(m)-MIBI or 99Tc(m)-tetrofosmin with tomographic rest images (250 MBq) acquired in the morning and exercise images (750 MBq) approximately 4 h later after pharmacological stress. Imaging technologists are concerned about continual exposure to 1000 MBq 99Tc(m) per study. Radiation doses were measured during rest (1.0 microSv, n = 18), exercise (2.5 microSv, n = 18) and stress administration (2.0 microSv, n = 16), giving a total dose of 5.5 microSv per combined cardiac study. We have previously shown that the average dose per radionuclide study (excluding myocardial perfusion studies) is 1.5 microSv. Although 5.5 microSv is higher, a technologist is highly unlikely to exceed current dose limits. New EC legislation, however, is expected to reduce these limits, which may lead to more classified workers. Pregnant technologists should avoid, if possible, combined cardiac studies, especially if performing other nuclear medicine duties.
E A Clarke; A Notghi; L K Harding
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Nuclear medicine communications     Volume:  18     ISSN:  0143-3636     ISO Abbreviation:  Nucl Med Commun     Publication Date:  1997 Jun 
Date Detail:
Created Date:  1997-09-30     Completed Date:  1997-09-30     Revised Date:  2008-11-21    
Medline Journal Info:
Nlm Unique ID:  8201017     Medline TA:  Nucl Med Commun     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  574-7     Citation Subset:  IM    
Department of Physics and Nuclear Medicine, City Hospital NHS Trust, Birmingham, UK.
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MeSH Terms
Adenosine / diagnostic use
Adrenergic beta-Agonists / diagnostic use
Allied Health Personnel*
Dobutamine / diagnostic use
Exercise Test
Heart / radionuclide imaging*
Nuclear Medicine
Occupational Exposure*
Organophosphorus Compounds
Organotechnetium Compounds
Radiation Dosage
Stress, Physiological
Technetium Tc 99m Sestamibi*
Reg. No./Substance:
0/Adrenergic beta-Agonists; 0/Organophosphorus Compounds; 0/Organotechnetium Compounds; 0/Radiopharmaceuticals; 0/technetium Tc 99m 1,2-bis(bis(2-ethoxyethyl)phosphino)ethane; 109581-73-9/Technetium Tc 99m Sestamibi; 34368-04-2/Dobutamine; 58-61-7/Adenosine

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