Document Detail


Are ferric compounds useful in treatment of iron deficiency anemia?
MedLine Citation:
PMID:  11196760     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The effect of ferric compounds in therapy of iron deficiency anemia is doubtful; however, the absorption of iron is not affected negatively by food or drugs. In our Well Baby Clinic, ferric polymaltose (6 mg/kg/d) was given to 59 infants (Group 1) and ferrous sulphate (same doses) was given to 64 infants (Group 2) (74 +/- 9 d, 70 +/- 7 d, respectively). These infants had iron deficiency anemia, and their therapy was continuous. Ferric polymaltose was not as effective as ferrous sulphate, although it increased hemoglobin and serum iron. Mean corpuscular volume and serum ferritin were not significantly changed after therapy. For this reason, we prefer to use only ferrous salts in therapy.
Authors:
A Arvas; E Gür
Publication Detail:
Type:  Clinical Trial; Comparative Study; Journal Article; Randomized Controlled Trial    
Journal Detail:
Title:  The Turkish journal of pediatrics     Volume:  42     ISSN:  0041-4301     ISO Abbreviation:  Turk. J. Pediatr.     Publication Date:    2000 Oct-Dec
Date Detail:
Created Date:  2001-01-25     Completed Date:  2001-02-15     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0417505     Medline TA:  Turk J Pediatr     Country:  Turkey    
Other Details:
Languages:  eng     Pagination:  352-3     Citation Subset:  IM    
Affiliation:
Social Pediatrics Unit, Department of Pediatrics, Istanbul University Cerrahpaşa Faculty of Medicine, Istanbul, Turkey.
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MeSH Terms
Descriptor/Qualifier:
Anemia, Iron-Deficiency / drug therapy*
Biological Availability
Female
Ferric Compounds / pharmacokinetics,  therapeutic use*
Ferrous Compounds / pharmacokinetics,  therapeutic use*
Humans
Infant
Male
Chemical
Reg. No./Substance:
0/Ferric Compounds; 0/Ferrous Compounds; 7720-78-7/ferrous sulfate; 79173-09-4/teferrol

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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