Document Detail

Are diurnal and nocturnal intraocular pressure measurements over 48 h justified?
MedLine Citation:
PMID:  23354356     Owner:  NLM     Status:  Publisher    
PURPOSE: Diurnal intraocular pressure (IOP) measurements are recommended in cases of visual field deterioration in glaucoma patients. In this study the rationale of 24 h versus 48 h IOP measurements was investigated. PATIENTS AND METHODS: Mean IOP and maximum IOP values were obtained in 80 patients over a period of 48 h. The IOP measurements (Goldmann tonometry) of day 1 and 2 (taken every 4 h) were compared. To reduce interindividual and intraindividual differences of measurements the statistical calculation took a tolerance level of ± 2 mmHg and ± 1 mmHg into account. RESULTS: Maximum IOP measurements were found to differ between 37.5 % and 65.0% respectively for right eyes and 28.8 % and 47.5% respectively for left eyes depending on the measurement tolerance (±2 mmHg or ±1 mmHg) between day 1 and day 2. Mean IOP values were found to differ by 25 % and 51.3 % respectively for right eyes and 26.3 % and 46.3% respectively for left eyes (± 2 or ± 1 mmHg in) between day 1 and day 2. A time-related clustering of extreme deviations could not be found but the maximum values from all patients were found to be roughly equally distributed over daytime and nighttime hours. CONCLUSIONS: Both maximum IOP and mean IOP measurements were found to differ by at least ± 2 or ± 1 mmHg between day 1 and 2 at a significant percentage and the maximum values did not peak at a predictable time point during the 48 h. Therefore, 48 h IOP measurements appear to be more reliable than 24 h measurements.
N Fischer; F Weinand; M U Kügler; S Scheel; B Lorenz
Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2013-1-27
Journal Detail:
Title:  Der Ophthalmologe : Zeitschrift der Deutschen Ophthalmologischen Gesellschaft     Volume:  -     ISSN:  1433-0423     ISO Abbreviation:  Ophthalmologe     Publication Date:  2013 Jan 
Date Detail:
Created Date:  2013-1-28     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9206148     Medline TA:  Ophthalmologe     Country:  -    
Other Details:
Languages:  GER     Pagination:  -     Citation Subset:  -    
Klinik und Poliklinik für Augenheilkunde, Justus-Liebig-Universität Gießen, Universitätsklinikum Gießen und Marburg GmbH, Standort Gießen, Friedrichstr. 18, 35392, Gießen, Deutschland.
Vernacular Title:
Sinnhaftigkeit von Tages-/Nacht-Augeninnendruckmessungen über 48 h.
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