Document Detail

Are dietary saturated, monounsaturated, and polyunsaturated fatty acids deposited to the same extent in adipose tissue of rabbits?
MedLine Citation:
PMID:  8338044     Owner:  NLM     Status:  MEDLINE    
The objective of this study was to determine the effect that different dietary fatty acids would have on the fatty acid composition of adipose tissue. Thirty adult rabbits were starved 3-4 wk to deplete adipose tissue stores. They were then refed five different fats (linseed, rapeseed, cocoa butter, palm, and safflower oils) to regain initial body weights. The fatty acids of the adipose tissue, in general, reflected the diet. Positive correlations between the amount of the five commonly consumed fatty acids (palmitic, stearic, oleic, linoleic, and linolenic acids) in the diet and their deposition into the adipose tissue were observed. All polyunsaturated and monounsaturated fatty acids were well incorporated into the adipose tissue, even linolenic acid. The deposition of dietary saturated fatty acids (ie stearic acid) was limited. Our data showed that the fatty acids of dietary fats may greatly affect adipose fatty acid composition. Thus, adipose stores of essential fatty acids can be greatly augmented by diet.
D S Lin; W E Connor; C W Spenler
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Publication Detail:
Type:  Comparative Study; Journal Article; Research Support, U.S. Gov't, P.H.S.    
Journal Detail:
Title:  The American journal of clinical nutrition     Volume:  58     ISSN:  0002-9165     ISO Abbreviation:  Am. J. Clin. Nutr.     Publication Date:  1993 Aug 
Date Detail:
Created Date:  1993-08-24     Completed Date:  1993-08-24     Revised Date:  2007-11-14    
Medline Journal Info:
Nlm Unique ID:  0376027     Medline TA:  Am J Clin Nutr     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  174-9     Citation Subset:  AIM; IM    
Department of Medicine, Oregon Health Sciences University, Portland 97201.
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MeSH Terms
Adipose Tissue / chemistry,  metabolism*
Dietary Fats / pharmacokinetics*
Dietary Fats, Unsaturated / metabolism*
Fatty Acids / analysis,  pharmacokinetics*
Fatty Acids, Monounsaturated / analysis,  pharmacokinetics
Fatty Acids, Unsaturated / analysis,  pharmacokinetics
Random Allocation
Tissue Distribution
Grant Support
Reg. No./Substance:
0/Dietary Fats; 0/Dietary Fats, Unsaturated; 0/Fatty Acids; 0/Fatty Acids, Monounsaturated; 0/Fatty Acids, Unsaturated

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