| Are claims of advertisements in medical journals supported by RCTs? | |
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MedLine Citation:
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PMID: 20103825 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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BACKGROUND: Claims made in advertisements in medical journals might not always be supported by high-quality evidence, and referenced studies may have been sponsored by the pharmaceutical industry itself. We studied to what extent randomised controlled trials (RCTs) support the claims in advertisements in leading medical journals. METHODS: Consecutive unique advertisements were selected from nine different medical journals, and evaluated by 250 medical students using a standardised score form. The quality of RCTs that were referenced in these advertisements was assessed with an instrument based on the Chalmers' score. RESULTS: 158 RCTs from 94 advertisements were used in the study. In total 55% of the RCTs had a high-quality score, 44% intermediate, and <1% had a low-quality score. Almost 40% of the RCTs had a high-quality score and at the same time supported the claim for which they were cited, while only 17% were also not sponsored by a pharmaceutical company. CONCLUSION: RCTs used to support claims in medical advertisements are often not a high-quality and independent source of evidence. This distracts from the credibility of claims in advertisements, even in the high-ranked journals. |
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Authors:
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L Heimans; A van Hylckama Vlieg; F W Dekker |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: The Netherlands journal of medicine Volume: 68 ISSN: 1872-9061 ISO Abbreviation: Neth J Med Publication Date: 2010 Jan |
Date Detail:
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Created Date: 2010-01-27 Completed Date: 2010-06-03 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 0356133 Medline TA: Neth J Med Country: Netherlands |
Other Details:
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Languages: eng Pagination: 46-9 Citation Subset: IM |
Affiliation:
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Department of Clinical Epidemiology, Leiden University Medical Center, Leiden, the Netherlands. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Advertising as Topic* Conflict of Interest* Drug Industry / ethics* Ethics, Medical* Evidence-Based Medicine Humans Journalism, Medical* Randomized Controlled Trials as Topic* / ethics |
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