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Are Preterm Infants at High Altitude at Greater Risk for the Development of Bronchopulmonary Dysplasia?
MedLine Citation:
PMID:  24072557     Owner:  NLM     Status:  Publisher    
Objectives: To assess the association between altitudes of neonatal intensive care units (NICUs) and the incidence of bronchopulmonary dysplasia (BPD) in preterm infants.Methods: Data from infants born at <32 weeks' gestation admitted to NICUs at high altitude (2200 m above sea level) between 2002 and 2011 were analyzed and compared with the data from a lower altitude NICU in Saudi Arabia.Results: Of 942 preterm infants admitted to the high altitude NICUs, 266 (28.2%) infants developed BPD. The incidence of BPD was significantly higher in infants admitted to the NICU at high altitude than in those at lower altitude (28.2 vs. 17.7%, respectively, p = 0.003). In multivariable analysis, high altitude was significantly associated with a higher risk of BPD (odds ratio: 0.54, 95% confidence interval: 0.36-0.81).Conclusion: Findings suggest that high altitude may increase the risk of BPD development among preterm infants.
Mohammed A Alshehri
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Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2013-9-26
Journal Detail:
Title:  Journal of tropical pediatrics     Volume:  -     ISSN:  1465-3664     ISO Abbreviation:  J. Trop. Pediatr.     Publication Date:  2013 Sep 
Date Detail:
Created Date:  2013-9-27     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8010948     Medline TA:  J Trop Pediatr     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Department of Child Health, College of Medicine, King Khalid University, Abha, Saudi Arabia 61413.
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