Document Detail

Are NORs easily translocated to deleted chromosomes?
MedLine Citation:
PMID:  669699     Owner:  NLM     Status:  MEDLINE    
The karyotype of two human meningiomas are reported in which, besides other aberrations, a deleted chromosome 1 and 6 could be observed. In these chromosomes most of the short arm is missing. After silver staining for the detection of NORs, not only the satellite regions of most of the acrocentric chromosomes were stained but also the deleted ends of chromosomes 1 and 6. Besides other explanations for this unusual NOR-staining, the possibility is discussed that NORs of acrocentric chromosomes are easily translocated to deleted chromosomes.
H Zankl; H Huwer
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Human genetics     Volume:  42     ISSN:  0340-6717     ISO Abbreviation:  Hum. Genet.     Publication Date:  1978 Jun 
Date Detail:
Created Date:  1978-09-15     Completed Date:  1978-09-15     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  7613873     Medline TA:  Hum Genet     Country:  GERMANY, WEST    
Other Details:
Languages:  eng     Pagination:  137-42     Citation Subset:  IM    
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MeSH Terms
Cell Nucleolus*
Chromosome Aberrations
Chromosome Deletion
Chromosomes, Human, 1-3
Chromosomes, Human, 6-12 and X
Meningeal Neoplasms / genetics*
Meningioma / genetics*
Translocation, Genetic*
Reg. No./Substance:

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